Area of research
Molecular Biology · Cancer Research
Research interest
Research interests include NF-κB Signaling Pathways, Cancer Immunotherapy and Biomarkers, RNA Research and Splicing, and Ubiquitin and proteasome pathways.
Angiogenesis and immune microenvironment in triple-negative breast cancer: Targeted therapy
Apolipoprotein A‐I Binding Protein: Functions, Mechanisms, and Therapeutic Targets in Neurological Disorders
Repulsive guidance molecules b (RGMb): molecular mechanism, function and role in diseases
BRD4 inhibitors broadly promote erastin-induced ferroptosis in different cell lines by targeting ROS and FSP1
The NEDD4-binding protein N4BP1 degrades mRNA substrates through the coding sequence independent of nonsense-mediated decay
AIBP protects drug-induced liver injury by inhibiting MAPK-mediated NR4A1 expression
NF-<i>κ</i>B: a mediator that promotes or inhibits angiogenesis in human diseases?
1,6-Hexanediol regulates angiogenesis via suppression of cyclin A1-mediated endothelial function
Identifying a locus in super-enhancer and its resident NFE2L1/MAFG as transcriptional factors that drive PD-L1 expression and immune evasion
Apolipoprotein A-I Binding Protein Inhibits the Formation of Infantile Hemangioma through Cholesterol-Regulated Hypoxia-Inducible Factor 1α Activation
N4BP1 regulates keratinocytes development and plays protective role in burn- and adhesive-related skin injury via MMP9
USP7 sustains an active epigenetic program via stabilizing MLL2 and WDR5 in diffuse large B‐cell lymphoma
The generation of PD-L1 and PD-L2 in cancer cells: From nuclear chromatin reorganization to extracellular presentation
Super-enhancer receives signals from the extracellular matrix to induce PD-L1-mediated immune evasion via integrin/BRAF/TAK1/ERK/ETV4 signaling
The endoribonuclease N4BP1 prevents psoriasis by controlling both keratinocytes proliferation and neutrophil infiltration
Hypoxia-induced RNASEH2A limits activation of cGAS-STING signaling in HCC and predicts poor prognosis
Ubiquitin-specific protease 7 is a druggable target that is essential for pancreatic cancer growth and chemoresistance
Multi‐omics analysis reveals the functional transcription and potential translation of enhancers
SPACE: a web server for linking chromatin accessibility with clinical phenotypes and the immune microenvironment in pan-cancer analysis
Pan-Cancer Analysis Reveals Disrupted Circadian Clock Associates With T Cell Exhaustion
A Tumor-Specific Super-Enhancer Drives Immune Evasion by Guiding Synchronous Expression of PD-L1 and PD-L2
HPV shapes tumor transcriptome by globally modifying the pool of RNA binding protein-binding motif
Targeting liquid-liquid phase separation in pancreatic cancer
A super-enhancer controls TGF- β signaling in pancreatic cancer through downregulation of TGFBR2
The C-terminal low-complexity domain involved in liquid–liquid phase separation is required for BRD4 function in vivo
Enhancer RNAs: a missing regulatory layer in gene transcription
Comprehensive transcriptome profiling in elderly cancer patients reveals aging‐altered immune cells and immune checkpoints
Orchestrating a biomarker panel with lncRNAs and mRNAs for predicting survival in pancreatic ductal adenocarcinoma
A super-enhancer maintains homeostatic expression of Regnase-1
Regnase-1, a rapid response ribonuclease regulating inflammation and stress responses