Area of research
Molecular Biology · Immunology
Research interest
Research interests include Cancer research, Biology, Genetic enhancement, Glycolysis, PI3K/AKT/mTOR pathway, and Cell biology.
A functional single-cell metabolic survey identifies Elovl1 as a target to enhance CD8+ T cell fitness in solid tumours
Nucleotide metabolism in cancer cells fuels a UDP-driven macrophage cross-talk, promoting immunosuppression and immunotherapy resistance
Targeting the bicarbonate transporter SLC4A4 overcomes immunosuppression and immunotherapy resistance in pancreatic cancer
Deletion of Lactate Dehydrogenase-A Impairs Oncogene-Induced Mouse Hepatocellular Carcinoma Development
Macrophage-derived glutamine boosts satellite cells and muscle regeneration
Podoplanin-Expressing Macrophages Promote Lymphangiogenesis and Lymphoinvasion in Breast Cancer
The mTOR and PP2A Pathways Regulate PHD2 Phosphorylation to Fine-Tune HIF1α Levels and Colorectal Cancer Cell Survival under Hypoxia
Macrophage Metabolism Controls Tumor Blood Vessel Morphogenesis and Metastasis
MET is required for the recruitment of anti-tumoural neutrophils
Tumour-educated circulating monocytes are powerful candidate biomarkers for diagnosis and disease follow-up of colorectal cancer
Liver-Specific Transcriptional Modules Identified by Genome-Wide In Silico Analysis Enable Efficient Gene Therapy in Mice and Non-Human Primates
Hyperactive PiggyBac Transposons for Sustained and Robust Liver-targeted Gene Therapy
Hyperfunctional coagulation factor IX improves the efficacy of gene therapy in hemophilic mice
Recent developments in transposon-mediated gene therapy