Area of research
Infectious Diseases · Virology
Research interest
Research interests include HIV Research and Treatment, HIV/AIDS drug development and treatment, SARS-CoV-2 and COVID-19 Research, and HIV/AIDS Research and Interventions.
HIV-1 viremia not suppressible by antiretroviral therapy can originate from large T cell clones producing infectious virus
HIV-1 in lymph nodes is maintained by cellular proliferation during antiretroviral therapy
Combined HIV-1 sequence and integration site analysis informs viral dynamics and allows reconstruction of replicating viral ancestors
Proviruses with identical sequences comprise a large fraction of the replication-competent HIV reservoir
Ex vivo activation of CD4+ T-cells from donors on suppressive ART can lead to sustained production of infectious HIV-1 from a subset of infected cells
Clonally expanded CD4 <sup>+</sup> T cells can produce infectious HIV-1 in vivo
Quantification of HIV-1 latency reversal in resting CD4 <sup>+</sup> T cells from patients on suppressive antiretroviral therapy