Area of research
Cancer Research · Oncology
Research interest
Research interests include Cancer Genomics and Diagnostics, Cancer Immunotherapy and Biomarkers, Genetic factors in colorectal cancer, and Genomics and Rare Diseases.
Tumour-informed liquid biopsies to monitor advanced melanoma patients under immune checkpoint inhibition
Detection of circulating cell-free HPV DNA of 13 HPV types for patients with cervical cancer as potential biomarker to monitor therapy response and to detect relapse
Multicentric pilot study to standardize clinical whole exome sequencing (WES) for cancer patients
Clinical outcome of biomarker-guided therapies in adult patients with tumors of the nervous system
Biallelic MAD2L1BP (p31comet) mutation is associated with mosaic aneuploidy and juvenile granulosa cell tumors
The DKTK EXLIQUID consortium – exploiting liquid biopsies to advance cancer precision medicine for molecular tumor board patients
Trailblazing precision medicine in Europe: A joint view by Genomic Medicine Sweden and the Centers for Personalized Medicine, ZPM, in Germany
Targeting extracellular and juxtamembrane FGFR2 mutations in chemotherapy-refractory cholangiocarcinoma
Cancer immune control needs senescence induction by interferon-dependent cell cycle regulator pathways in tumours
Dynamics of cell-free tumour DNA correlate with treatment response of head and neck cancer patients receiving radiochemotherapy
Next-Generation Sequencing of Advanced GI Tumors Reveals Individual Treatment Options
PET/MRI and genetic intrapatient heterogeneity in head and neck cancers
Multi-omics discovery of exome-derived neoantigens in hepatocellular carcinoma
A Non-interventional Clinical Trial Assessing Immune Responses After Radiofrequency Ablation of Liver Metastases From Colorectal Cancer
Radiogenomics in head and neck cancer: correlation of radiomic heterogeneity and somatic mutations in TP53, FAT1 and KMT2D
Circulating cell-free DNA: A potential biomarker to differentiate inflammation and infection during radiochemotherapy
First case report of malignant peritoneal mesothelioma and oral verrucous carcinoma in a patient with a germline PTEN mutation: a combination of extremely rare diseases with probable further implications
Childhood cancer predisposition syndromes—A concise review and recommendations by the Cancer Predisposition Working Group of the Society for Pediatric Oncology and Hematology
Organ preservation in rectal cancer – Challenges and future strategies
Personalized peptide vaccine-induced immune response associated with long-term survival of a metastatic cholangiocarcinoma patient
PRRT2 Mutations are the major cause of benign familial infantile seizures