Area of research
Pulmonary and Respiratory Medicine · Cancer Research
Research interest
Research interests include Sarcoma Diagnosis and Treatment, Cancer Genomics and Diagnostics, Cardiac tumors and thrombi, and Cancer-related molecular mechanisms research.
Comprehensive DSRCT multi‐omics analyses unveil CACNA2D2 as a diagnostic hallmark and super‐enhancer‐driven EWSR1::WT1 signature gene
Targeted long-read sequencing of the Ewing sarcoma 6p25.1 susceptibility locus identifies germline-somatic interactions with EWSR1-FLI1 binding
Integrative gene network and functional analyses identify a prognostically relevant key regulator of metastasis in Ewing sarcoma
Chromosome 8 gain drives cancer progression by hijacking the translation factor 4E-BP1 sensitizing for targeted CDK4/6 inhibition
Sarcoma classification by DNA methylation profiling
Translational evidence for RRM2 as a prognostic biomarker and therapeutic target in Ewing sarcoma
Therapeutic targeting of the PLK1-PRC1-axis triggers cell death in genomically silent childhood cancer
Translational evidence for RRM2 as a prognostic biomarker and therapeutic target in Ewing sarcoma
Systems biology analysis identifies TCF7L1 as a key regulator of metastasis in Ewing sarcoma
Oncogenic hijacking of a developmental transcription factor evokes vulnerability toward oxidative stress in Ewing sarcoma
A comparative view on the expression patterns of PD-L1 and PD-1 in soft tissue sarcomas
High Specificity of BCL11B and GLG1 for EWSR1-FLI1 and EWSR1-ERG Positive Ewing Sarcoma
Western Blot Analysis in Ewing Sarcoma
Tissue Preservation and FFPE Samples: Optimized Nucleic Acids Isolation in Ewing Sarcoma
Publisher Correction: Oncogenic hijacking of a developmental transcription factor evokes vulnerability toward oxidative stress in Ewing sarcoma
Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity
Cooperation of cancer drivers with regulatory germline variants shapes clinical outcomes
DNA methylation profiling distinguishes Ewing-like sarcoma with EWSR1–NFATc2 fusion from Ewing sarcoma
Targeting the CALCB/RAMP1 axis inhibits growth of Ewing sarcoma
DNA methylation-based profiling of uterine neoplasms: a novel tool to improve gynecologic cancer diagnostics
Gene expression and immunohistochemical analyses identify SOX2 as major risk factor for overall survival and relapse in Ewing sarcoma patients
Hippo pathway effectors YAP1/TAZ induce an <i>EWS–FLI1</i> ‐opposing gene signature and associate with disease progression in Ewing sarcoma
Integrative clinical transcriptome analysis reveals <i>TMPRSS2‐ERG</i> dependency of prognostic biomarkers in prostate adenocarcinoma
Hippo pathway effectors YAP1/TAZ induce a EWS-FLI1-opposing gene signature and associate with disease progression in Ewing Sarcoma
Oncogenic hijacking of a developmental transcription factor evokes therapeutic vulnerability for ROS-induction in Ewing sarcoma
Expression patterns of PD-L1 and PD-1 provide rationales for immune checkpoint inhibition in soft tissue sarcomas
Biomarker-based outcome prediction in prostate adenocarcinoma depends on the <i>TMPRSS2-ERG</i> status
Functional genomics identifies AMPD2 as a new prognostic marker for undifferentiated pleomorphic sarcoma
Targeting the CALCB/RAMP1-axis inhibits growth of Ewing sarcoma