Area of research
Surgery · Molecular Biology
Research interest
Research interests include Biology, Cancer research, LGR5, Wnt signaling pathway, Cell biology, and Stem cell.
Aspirin reprogrammes colorectal cancer cell metabolism and sensitises to glutaminase inhibition
Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia
Retrograde movements determine effective stem cell numbers in the intestine
Epithelial TGFβ engages growth-factor signalling to circumvent apoptosis and drive intestinal tumourigenesis with aggressive features
Aspirin reprogrammes colorectal cancer cell metabolism and sensitises to glutaminase inhibition
NOTUM from Apc-mutant cells biases clonal competition to initiate cancer
Oncogenic BRAF, unrestrained by TGFβ-receptor signalling, drives right-sided colonic tumorigenesis
Expression of R-Spondin 1 in Apc Mice Suppresses Growth of Intestinal Adenomas by Altering Wnt and Transforming Growth Factor Beta Signaling