Area of research
Epidemiology · Physiology
Research interest
Research interests include Biology, Mitophagy, PINK1, Autophagy, Neuroscience, and Ubiquitin ligase.
Mitochondrial complex I deficiency induces Alzheimer's disease–like signatures that are reversible by targeted therapy
Activation of endogenous PRKN by structural derepression is linked to increased turnover of the E3 ubiquitin ligase
Alterations of PINK1-PRKN signaling in mice during normal aging
Aggregation dynamics of a 150 kDa Aβ42 oligomer: Insights from cryo electron microscopy and multimodal analysis
Basal activity of PINK1 and PRKN in cell models and rodent brain
A common pathway for detergent-assisted oligomerization of Aβ42
Structural Model for Self-Limiting β-strand Arrangement Within an Alzheimer’s Amyloid-β Oligomer
Sensitive ELISA-based detection method for the mitophagy marker p-S65-Ub in human cells, autopsy brain, and blood samples
Sensitive ELISA-based detection method for the mitophagy marker p-S65-Ub in human cells, autopsy brain, and blood samples
Out-of-Register Parallel β-Sheets and Antiparallel β-Sheets Coexist in 150-kDa Oligomers Formed by Amyloid-β(1–42)
Conserved brain myelination networks are altered in Alzheimer's and other neurodegenerative diseases