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Karthik Nagapudi

Amgen (United States) · US
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Area of research
Pharmaceutical Science · Materials Chemistry
Research interest
Research interests include Materials science, Pharmacology, Pharmacokinetics, Chemistry, Amorphous solid, and Dissolution.
h-index
citations
440
works
24
NIH funding
primary concept
email

Recent publications

Engineering a protease-stable, oral single-domain antibody to inhibit IL-23 signaling
Proceedings of the National Academy of Sciences 2025cited by 8position: middledoi
Assessing the impacts of drug loading and polymer type on dissolution behavior and diffusive flux of GDC-6893 amorphous solid dispersions
Journal of Pharmaceutical Sciences 2025cited by 1position: middledoi
Investigation of the suitability of utilizing plasma concentration as a surrogate to understand lung exposure of inhaled drug in rats: Different delivery methods of fluticasone propionate
Journal of Pharmaceutical Sciences 2025cited by 1position: middledoi
Engineering ERα degraders with pleiotropic ubiquitin ligase ligands maximizes therapeutic efficacy by co-opting distinct effector ligases
Cell chemical biology 2025cited by 1position: middledoi
Exploring a new approach in biopharmaceutics to improve the estimation of stomach solubilization from the mathematical model with a single stomach compartment setting: The impact of stomach solubilization on the food effect of quazepam
Journal of Pharmaceutical Sciences 2025cited by 0position: middledoi
Evaluating Utilization of Tiny-TIM to Assess the Effect of Food on the Absorptions of Oral Drugs and Its Application on Biopharmaceutical Modeling
Journal of Pharmaceutical Sciences 2024cited by 9position: middledoi
The effect of unloading and ejection conditions on the properties of pharmaceutical tablets
International Journal of Pharmaceutics 2024cited by 3position: middledoi
Exploring the Use of a Kinetic pH Calculation to Correct the ACAT Model with a Single Stomach Compartment Setting: Impact of Stomach Setting on Food Effect Prediction for Basic Compounds
Journal of Pharmaceutical Sciences 2023cited by 3position: middledoi
Assessing the Interrelationship of Microstructure, Properties, Drug Release Performance, and Preparation Process for Amorphous Solid Dispersions Via Noninvasive Imaging Analytics and Material Characterization
Pharmaceutical Research 2022cited by 22position: middledoi
Capsule-Based dry powder inhaler evaluation using CFD-DEM simulations and next generation impactor data
European Journal of Pharmaceutical Sciences 2022cited by 18position: middledoi
Effect of magnesium stearate surface coating method on the aerosol performance and permeability of micronized fluticasone propionate
International Journal of Pharmaceutics 2022cited by 13position: middledoi
Impact of drug loading on the compaction properties of itraconazole-PVPVA amorphous solid dispersions
International Journal of Pharmaceutics 2022cited by 10position: middledoi
Release Mechanisms and Practical Percolation Threshold for Long-acting Biodegradable Implants: An Image to Simulation Study
Journal of Pharmaceutical Sciences 2021cited by 20position: middledoi
Effect of Lipidic Excipients on the Particle Properties and Aerosol Performance of High Drug Load Spray Dried Particles for Inhalation
Journal of Pharmaceutical Sciences 2021cited by 13position: middledoi
Utilizing Tiny-TIM to Assess the Effect of Acid-Reducing Agents on the Absorption of Orally Administered Drugs
Journal of Pharmaceutical Sciences 2021cited by 12position: middledoi
Impact of polymer type, ASD loading and polymer-drug ratio on ASD tablet disintegration and drug release
International Journal of Pharmaceutics 2020cited by 38position: middledoi
Evaluating the Pharmacokinetics and Systemic Effects of a Permeability Enhancer Sodium N-[8-(2-hydroxybenzoyl)amino] Caprylate in Rats
Journal of Pharmaceutical Sciences 2020cited by 5position: middledoi
Simple, Scalable Mechanosynthesis of Metal-Organic Frameworks Using Liquid-Assisted Resonant Acoustic Mixing (LA-RAM)
ChemRxiv 2020cited by 4position: middledoi
Special Section on Pharmacokinetic and Drug Metabolism Properties of Novel Therapeutic Modalities–Minireview
Drug Metabolism and Disposition 2019cited by 121position: middledoi
In Situ Characterization of Waters of Hydration in a Variable-Hydrate Active Pharmaceutical Ingredient Using <sup>35</sup>Cl Solid-State NMR and X-ray Diffraction
Crystal Growth & Design 2019cited by 27position: middledoi
Exploring Multicompartment Plug Flow–Based Model Approach in Biopharmaceutics: Impact of Stomach Setting and the Estimation of the Fraction Absorbed of Orally Administered Basic Drugs
Journal of Pharmaceutical Sciences 2019cited by 7position: middledoi
Impact of Method of Preparation of Amorphous Solid Dispersions on Mechanical Properties: Comparison of Coprecipitation and Spray Drying
Journal of Pharmaceutical Sciences 2018cited by 56position: lastdoi
Effect of Microenvironmental pH Modulation on the Dissolution Rate and Oral Absorption of the Salt of a Weak Acid – Case Study of GDC-0810
Pharmaceutical Research 2018cited by 20position: lastdoi
Investigation of Drug Delivery in Rats via Subcutaneous Injection: Case Study of Pharmacokinetic Modeling of Suspension Formulations
Journal of Pharmaceutical Sciences 2018cited by 14position: middledoi
A rational approach towards development of amorphous solid dispersions: Experimental and computational techniques
International Journal of Pharmaceutics 2017cited by 41position: lastdoi

Grants

No grants ingested yet.

Frequent collaborators

Po‐Chang Chiang · Gene Therapy Laboratory7 papers (2018–2025)Hao Hou · Shenzhen University6 papers (2018–2025)Jia Liu · China Pharmaceutical University4 papers (2023–2025)Michael Dolton · San-Ei Gen F.F.I (Japan)4 papers (2019–2025) · 3 papers (2022–2024)Jia Liu · Nanjing University of Chinese Medicine3 papers (2018–2025)Joseph W. Lubach · Gene Therapy Laboratory3 papers (2017–2025) · 3 papers (2017–2025) · 3 papers (2018–2024)Ariel R. Muliadi · Gene Therapy Laboratory3 papers (2018–2024) · 2 papers (2021–2022) · 2 papers (2017–2019)Matthew R. Durk · Gene Therapy Laboratory2 papers (2020–2025) · 2 papers (2021–2022) · 2 papers (2018–2022) · 2 papers (2021–2022)Evelyn Yanez · Amgen (United States)2 papers (2021–2022)Nivedita Shetty · Purdue University West Lafayette2 papers (2021–2025) · 2 papers (2020–2025) · 1 papers (2025–2025)
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