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Ronald R. Breaker

Université Alassane Ouattara · US
🔎 Find collaborators in Molecular Biology · Genetics →
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Area of research
Molecular Biology · Genetics
Research interest
Research interests include RNA and protein synthesis mechanisms, RNA modifications and cancer, Bacterial Genetics and Biotechnology, and Advanced biosensing and bioanalysis techniques.
h-index
106
citations
39,393
works
298
NIH funding
primary concept
email

Recent publications

Miniature NAD<sup>+</sup>-II riboswitches control bacterial genes for nicotinamide salvage and de novo NAD<sup>+</sup> biosynthesis.
2026cited by 0position: contributordoi
Guanidine aptamers are present in vertebrate RNAs associated with calcium signaling and neuromuscular function.
2025cited by 2position: contributordoi
Implications for OLE RNA as a natural integral membrane RNA.
2025cited by 1position: contributordoi
Evidence that ribosomal protein bS21 is a component of the OLE ribonucleoprotein complex.
2025cited by 1position: contributordoi
Decoding the Complex Functional Landscape of the <i>ykkC</i> Riboswitches.
2025cited by 0position: contributordoi
Author Correction: Guanidine aptamers are present in vertebrate RNAs associated with calcium signaling and neuromuscular function.
2025cited by 0position: contributordoi
The discovery of novel noncoding RNAs in 50 bacterial genomes
Nucleic Acids Research 2024cited by 18position: lastdoi
The discovery of novel noncoding RNAs in 50 bacterial genomes.
2024cited by 15position: contributordoi
Genetic disruption of the bacterial <i>raiA</i> motif noncoding RNA causes defects in sporulation and aggregation.
2024cited by 9position: contributordoi
Disruption of the bacterial OLE RNP complex impairs growth on alternative carbon sources.
2024cited by 8position: contributordoi
Bioinformatic prediction of proteins relevant to functions of the bacterial OLE ribonucleoprotein complex.
2024cited by 7position: contributordoi
Disruption of the bacterial OLE RNP complex impairs growth on alternative carbon sources
PNAS Nexus 2024cited by 6position: lastdoi
Bioinformatic prediction of proteins relevant to functions of the bacterial OLE ribonucleoprotein complex
mSphere 2024cited by 6position: lastdoi
Improved methods for genetic manipulation of the alkaliphile Halalkalibacterium halodurans
Frontiers in Microbiology 2024cited by 3position: lastdoi
Engineered Branaplam Aptamers Exploit Structural Elements from Natural Riboswitches
ACS Chemical Biology 2024cited by 2position: lastdoi
Engineered Branaplam Aptamers Exploit Structural Elements from Natural Riboswitches.
2024cited by 1position: contributordoi
Discovering riboswitches: the past and the future.
2023cited by 200position: contributordoi
Riboswitches
Current Biology 2023cited by 60position: lastdoi
Exploiting natural riboswitches for aptamer engineering and validation
Nucleic Acids Research 2023cited by 50position: lastdoi
Exploiting natural riboswitches for aptamer engineering and validation.
2023cited by 39position: contributordoi
Evidence that OLE RNA is a component of a major stress-responsive ribonucleoprotein particle in extremophilic bacteria.
2023cited by 15position: contributordoi
Evidence that OLE RNA is a component of a major stress‐responsive ribonucleoprotein particle in extremophilic bacteria
Molecular Microbiology 2023cited by 14position: firstdoi
A spermidine riboswitch class in bacteria exploits a close variant of an aptamer for the enzyme cofactor S-adenosylmethionine
Cell Reports 2023cited by 12position: lastdoi
A spermidine riboswitch class in bacteria exploits a close variant of an aptamer for the enzyme cofactor S-adenosylmethionine.
2023cited by 9position: contributordoi
8-oxoguanine riboswitches in bacteria detect and respond to oxidative DNA damage.
2023cited by 9position: contributordoi
Screening for small molecule inhibitors of SAH nucleosidase using an SAH riboswitch
Analytical Biochemistry 2023cited by 7position: lastdoi
In vitro Selection and in vivo Testing of Riboswitch-inspired Aptamers
BIO-PROTOCOL 2023cited by 6position: lastdoi
A conserved uORF in the ilvBNC mRNA of Corynebacterium species regulates ilv operon expression
Microbial Genomics 2023cited by 3position: lastdoi
Discovering riboswitches: the past and the future
Trends in Biochemical Sciences 2022cited by 254position: lastdoi
The Biochemical Landscape of Riboswitch Ligands
Biochemistry 2022cited by 115position: firstdoi

Grants

EAGER: A Model System for Soil Microbial Communities
NSF1243671$300,0002013–2015PIRePORTER
Engineering Genetic Control Mechanisms of Riboswitches
NSF0323510$635,4632003–2006PIRePORTER
The Role of Riboswitches in Bacillus Information Control
NSF0324045$74,7112003–2004PIRePORTER
Bio-QuBIC: Engineering Molecular Logic Gates Using Nucleic Acids
NSF0129939$399,3492001–2004PIRePORTER

Frequent collaborators

· 36 papers (2019–2026)Madeline E. Sherlock · University of California, Santa Cruz13 papers (2016–2022)Kimberly A. Harris · Yale University11 papers (2015–2024)Ruben M. Atilho · Yale University10 papers (2016–2022)James W. Nelson · Broad Institute9 papers (2013–2017)Zasha Weinberg · Telstra (Australia)9 papers (2013–2021)Sanshu Li · Huaqiao University8 papers (2012–2017)Ronald Breaker · Yale Cancer Center8 papers (2022–2026)Narasimhan Sudarsan · Howard Hughes Medical Institute8 papers (2013–2022)Sarah N. Malkowski · Yale University7 papers (2016–2022)Gayan Mirihana Arachchilage · Howard Hughes Medical Institute7 papers (2017–2022) · 7 papers (2015–2020) · 6 papers (2015–2019) · 5 papers (2020–2024) · 5 papers (2019–2024) · 5 papers (2020–2024)Harini Sadeeshkumar · Lawrence Berkeley National Laboratory5 papers (2018–2023)Phillip J. McCown · University of Michigan–Ann Arbor5 papers (2012–2017) · 5 papers (2015–2021) · 4 papers (2017–2021)
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