Area of research
Oncology · Genetics
Research interest
Research interests include HER2/EGFR in Cancer Research, Monoclonal and Polyclonal Antibodies Research, BRCA gene mutations in cancer, and Breast Cancer Treatment Studies.
Refining breast cancer genetic risk and biology through multi-ancestry fine-mapping analyses of 192 risk regions
Genome-wide association analyses of breast cancer in women of African ancestry identify new susceptibility loci and improve risk prediction
Early Detection of Ovarian Cancer Using Cell-Free DNA Fragmentomes and Protein Biomarkers
721MO Phase I, two-part, multicenter first-in-human (FIH) study of TORL-1-23: A novel claudin 6 (CLDN6) targeting antibody drug conjugate (ADC) in patient with advanced solid tumors
Impact of CCND1 amplification on the prognosis of hormone receptor–positive, HER2-negative breast cancer patients—correlation of clinical and pathological markers
Case-Case Genome-Wide Analyses Identify Subtype-Informative Variants That Confer Risk for Breast Cancer
ESMO expert consensus statements (ECS) on the definition, diagnosis, and management of HER2-low breast cancer
Preclinical Efficacy of the Antibody–Drug Conjugate CLDN6–23-ADC for the Treatment of CLDN6-Positive Solid Tumors
Tumor biomarkers and efficacy in patients treated with trastuzumab emtansine + pertuzumab versus standard of care in HER2-positive early breast cancer: an open-label, phase III study (KRISTINE)
Initial results of dose finding in a first-in-human phase 1 study of a novel Claudin 6 (CLDN6) targeted antibody drug conjugate (ADC) TORL-1-23 in patients with advanced solid tumors.
Polygenic risk scores for prediction of breast cancer risk in women of African ancestry: a cross-ancestry approach
Spatial proteomic characterization of HER2-positive breast tumors through neoadjuvant therapy predicts response
Evaluating Polygenic Risk Scores for Breast Cancer in Women of African Ancestry
A careful reassessment of anthracycline use in curable breast cancer
Cross-ancestry GWAS meta-analysis identifies six breast cancer loci in African and European ancestry women
Deep learning-enabled breast cancer hormonal receptor status determination from base-level H&E stains
Pathologic and molecular responses to neoadjuvant trastuzumab and/or lapatinib from a phase II randomized trial in HER2-positive breast cancer (TRIO-US B07)
A meta-analysis of genome-wide association studies of multiple myeloma among men and women of African ancestry
Case-Based Review and Clinical Guidance on the Use of Genomic Assays for Early-Stage Breast Cancer: Breast Cancer Therapy Expert Group (BCTEG)
Abstract P4-07-01: Tumor expression and microenvironment in HER2-positive breast cancer before and on HER2-targeted therapy: Analysis of microarray expression data from the TRIO-US B07 trial
Potent Cell-Cycle Inhibition and Upregulation of Immune Response with Abemaciclib and Anastrozole in neoMONARCH, Phase II Neoadjuvant Study in HR+/HER2− Breast Cancer
Clonal replacement and heterogeneity in breast tumors treated with neoadjuvant HER2-targeted therapy
Publisher Correction: Clonal replacement and heterogeneity in breast tumors treated with neoadjuvant HER2-targeted therapy
Human Epidermal Growth Factor Receptor 2 Testing in Breast Cancer: American Society of Clinical Oncology/College of American Pathologists Clinical Practice Guideline Focused Update
Human Epidermal Growth Factor Receptor 2 Testing in Breast Cancer: American Society of Clinical Oncology/College of American Pathologists Clinical Practice Guideline Focused Update
Integrated Genomic, Epigenomic, and Expression Analyses of Ovarian Cancer Cell Lines
Discovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African Ancestry Anthropometry Genetics Consortium
A functionally significant SNP in TP53 and breast cancer risk in African-American women
Characterizing Genetic Susceptibility to Breast Cancer in Women of African Ancestry
Genome-wide association studies in women of African ancestry identified 3q26.21 as a novel susceptibility locus for oestrogen receptor negative breast cancer