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B Bernstein

Harvard University · US
Area of research
Molecular Biology
Research interest
Research interests include Epigenetics and DNA Methylation, Genomics and Chromatin Dynamics, Single-cell and spatial transcriptomics, and Cancer-related gene regulation.
h-index
118
citations
135,426
works
2,597
NIH funding
primary concept
Biology
email

Recent publications

Programs, origins and immunomodulatory functions of myeloid cells in glioma
Nature 2025cited by 92position: lastdoi
The Somatic Mosaicism across Human Tissues Network
Nature 2025cited by 39position: middledoi
TMOD-12. Preclinical and clinical assessment of chemoradiation after mutant IDH inhibitor treatment in IDH-mutant glioma
Neuro-Oncology 2025cited by 0position: middledoi
Dissection of a CTCF topological boundary uncovers principles of enhancer-oncogene regulation
Molecular Cell 2024cited by 34position: lastdoi
Exposure of iPSC-derived human microglia to brain substrates enables the generation and manipulation of diverse transcriptional states in vitro
Nature Immunology 2023cited by 148position: middledoi
The EN-TEx resource of multi-tissue personal epigenomes & variant-impact models
Cell 2023cited by 80position: middledoi
Mitochondrial variant enrichment from high-throughput single-cell RNA sequencing resolves clonal populations
Nature Biotechnology 2022cited by 145position: middledoi
Single-cell RNA sequencing identifies a paracrine interaction that may drive oncogenic notch signaling in human adenoid cystic carcinoma
Cell Reports 2022cited by 24position: middledoi
Author Correction: Expanded encyclopaedias of DNA elements in the human and mouse genomes
Nature 2022cited by 21position: middledoi
A resource for generating and manipulating human microglial states in vitro
bioRxiv (Cold Spring Harbor Laboratory) 2022cited by 11position: middledoi
Author Correction: Perspectives on ENCODE
Nature 2022cited by 0position: middledoi
Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing
Cell 2021cited by 736position: middledoi
Epigenetic silencing by SETDB1 suppresses tumour intrinsic immunogenicity
Nature 2021cited by 355position: lastdoi
Mitochondrial variant enrichment from high-throughput single-cell RNA-seq resolves clonal populations
bioRxiv (Cold Spring Harbor Laboratory) 2021cited by 14position: middledoi
Expanded encyclopaedias of DNA elements in the human and mouse genomes
Nature 2020cited by 2,541position: middledoi
Evaluation of SARS-CoV-2 serology assays reveals a range of test performance
Nature Biotechnology 2020cited by 299position: middledoi
Large-Scale Topological Changes Restrain Malignant Progression in Colorectal Cancer
Cell 2020cited by 252position: lastdoi
Perspectives on ENCODE
Nature 2020cited by 222position: middledoi
Single-cell RNA-seq reveals developmental plasticity with coexisting oncogenic states and immune evasion programs in ETP-ALL
Blood 2020cited by 94position: middledoi
Gain-of-Function Genetic Alterations of G9a Drive Oncogenesis
Cancer Discovery 2020cited by 73position: middledoi
Data-Driven Polymer Model for Mechanistic Exploration of Diploid Genome Organization
Biophysical Journal 2020cited by 69position: middledoi
ETMR-17. SINGLE-CELL TRANSCRIPTOME ANALYSIS OF ETMR PATIENT SAMPLES
Neuro-Oncology 2020cited by 0position: middledoi
An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma
Cell 2019cited by 2,788position: middledoi
Single-Cell RNA-Seq Reveals AML Hierarchies Relevant to Disease Progression and Immunity
Cell 2019cited by 1,170position: lastdoi
Resolving medulloblastoma cellular architecture by single-cell genomics
Nature 2019cited by 426position: middledoi
Altered chromosomal topology drives oncogenic programs in SDH-deficient GISTs
Nature 2019cited by 258position: lastdoi
Re-programing Chromatin with a Bifunctional LSD1/HDAC Inhibitor Induces Therapeutic Differentiation in DIPG
Cancer Cell 2019cited by 188position: middledoi
Enhancer signatures stratify and predict outcomes of non-functional pancreatic neuroendocrine tumors
Nature Medicine 2019cited by 184position: middledoi
Corrupted coordination of epigenetic modifications leads to diverging chromatin states and transcriptional heterogeneity in CLL
Nature Communications 2019cited by 84position: middledoi
Publisher Correction: Enhancer signatures stratify and predict outcomes of non-functional pancreatic neuroendocrine tumors
Nature Medicine 2019cited by 5position: middledoi

Grants

Collaborative Research: The Comparative Morpho-Syntax of Appalachian English
NSF0617210$38,1802006–2009PIRePORTER
International Decade of Hazard Reduction: Planning Activities--Phase 2
NSF8611854$20,0001986–1987PIRePORTER
Topics in Theoretical Plasma Physics
NSF8405397$64,7211984–1987PIRePORTER
Molecular Beam and Laser Studies of Oriented Molecule Reactions (Chemistry)
NSF8316205$633,4721983–1987PIRePORTER
Propagation of Electromagnetic Waves in Plasmas Within the Framework of Geometric Optics
NSF8300792$8,0001983–1986PIRePORTER
Propagation of Electromagnetic Waves in Plasmas Within the Framework of Geometric Optics
NSF8202723$5,0001982–1983PIRePORTER
Topics in Theoretical Plasma Physics
NSF8107291$97,4081981–1984PIRePORTER
Master Grant For Chemistry Projects Under Grant Administration Agreement No.8
NSF7850008$2,695,4241979–1982PIRePORTER
Master Grant For Chemistry Projects Under Grant Administration Agreement No.8
NSF7950008$1,690,4501979–1982PIRePORTER
Topics in Theoretical Plasma Physics
NSF7808433$84,6751978–1981PIRePORTER
Molecular Beam Scattering
NSF7304940$380,0001973–1978PIRePORTER

Frequent collaborators

Shawn Gillespie · Stanford University14 papers (2013–2019)Mario L. Suvà · Harvard University10 papers (2012–2025)Yotam Drier · MGH Institute of Health Professions10 papers (2015–2022)Noam Shoresh · Broad Institute8 papers (2013–2020)Peter van Galen · Broad Institute8 papers (2015–2022)Charles B. Epstein · Broad Institute7 papers (2012–2023)Anoop P. Patel · Duke Cancer Institute7 papers (2013–2018)Oren Ram · Hebrew University of Jerusalem6 papers (2012–2015)Alex K. Shalek · Broad Institute6 papers (2013–2025)Tyler E. Miller · University Hospitals of Cleveland6 papers (2016–2025)Jon C. Aster · Harvard University6 papers (2016–2022)Alexander Meissner · Max Planck Institute for Molecular Genetics6 papers (2013–2019)Brian B. Liau · Broad Institute6 papers (2015–2020)Julia A. Verga · Center for Cancer Research5 papers (2018–2025)Russell J.H. Ryan · University of Michigan5 papers (2014–2017)Esther Rheinbay · Harvard University5 papers (2012–2014)Aviv Regev · Moscow Institute of Thermal Technology5 papers (2012–2017)Ross L. Levine · Leukemia and Lymphoma Society5 papers (2012–2017)Sarah E. Johnstone · Leicester General Hospital5 papers (2017–2020)Caleb A. Lareau · Gladstone Institutes5 papers (2017–2022)