Area of research
Molecular Biology · Epidemiology
Research interest
Research interests include PI3K/AKT/mTOR pathway, Biology, Cell biology, Skeletal muscle, mTORC1, and RPTOR.
Muscle mTOR controls iron homeostasis and ferritinophagy via NRF2, HIFs and AKT/PKB signaling pathways
Pharmacological inhibition of HDAC6 improves muscle phenotypes in dystrophin-deficient mice by downregulating TGF-β via Smad3 acetylation
H2A.Z is dispensable for both basal and activated transcription in post-mitotic mouse muscles
Increased Serpina3n release into circulation during glucocorticoid‐mediated muscle atrophy
Lack of muscle mTOR kinase activity causes early onset myopathy and compromises whole‐body homeostasis
Resistance exercise initiates mechanistic target of rapamycin (mTOR) translocation and protein complex co-localisation in human skeletal muscle
mTOR inactivation in myocardium from infant mice rapidly leads to dilated cardiomyopathy due to translation defects and p53/JNK-mediated apoptosis
The metabolic checkpoint kinase mTOR is essential for IL-15 signaling during the development and activation of NK cells
Arrest of Myelination and Reduced Axon Growth When Schwann Cells Lack mTOR