Area of research
Physiology · Neurology
Research interest
Research interests include Alzheimer's disease research and treatments, Neuroinflammation and Neurodegeneration Mechanisms, Criminal Law and Policy, and Neuroscience and Neuropharmacology Research.
Neuroinflammation generated by HIV-infected microglia promotes dysfunction and death of neurons in human brain organoids
Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration
Acetylated tau inhibits chaperone-mediated autophagy and promotes tau pathology propagation in mice
A MAC2-positive progenitor-like microglial population is resistant to CSF1R inhibition in adult mouse brain
Pathogenic Tau Impairs Axon Initial Segment Plasticity and Excitability Homeostasis
A Comprehensive Resource for Induced Pluripotent Stem Cells from Patients with Primary Tauopathies
SIRT1 Deacetylates Tau and Reduces Pathogenic Tau Spread in a Mouse Model of Tauopathy
Scalable Production of iPSC-Derived Human Neurons to Identify Tau-Lowering Compounds by High-Content Screening
Acetylated Tau Obstructs KIBRA-Mediated Signaling in Synaptic Plasticity and Promotes Tauopathy-Related Memory Loss
Acetylated tau destabilizes the cytoskeleton in the axon initial segment and is mislocalized to the somatodendritic compartment
Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits
SIRT1 Deficiency in Microglia Contributes to Cognitive Decline in Aging and Neurodegeneration via Epigenetic Regulation of IL-1β
Argyrophilic grain disease differs from other tauopathies by lacking tau acetylation