Area of research
Molecular Biology · Cancer Research
Research interest
Research interests include Bioinformatics and Genomic Networks, Ubiquitin and proteasome pathways, Gene expression and cancer classification, and Cancer Genomics and Diagnostics.
Gemcitabine and cisplatin plus nivolumab as organ-sparing treatment for muscle-invasive bladder cancer: a phase 2 trial
NKG2A and HLA-E define an alternative immune checkpoint axis in bladder cancer
Integrative network analysis of early-stage lung adenocarcinoma identifies aurora kinase inhibition as interceptor of invasion and progression
Transcriptional Circuitry of NKX2-1 and SOX1 Defines an Unrecognized Lineage Subtype of Small-Cell Lung Cancer
Tumor-Infiltrating Myeloid Cells Confer <i>De Novo</i> Resistance to PD-L1 Blockade through EMT–Stromal and Tgfβ-Dependent Mechanisms
An integrative multiomic network model links lipid metabolism to glucose regulation in coronary artery disease
Integrated Proteogenomic Characterization across Major Histological Types of Pediatric Brain Cancer
Transformative Network Modeling of Multi-omics Data Reveals Detailed Circuits, Key Regulators, and Potential Therapeutics for Alzheimer’s Disease
Multiscale causal networks identify VGF as a key regulator of Alzheimer’s disease
Enteric involvement in hospitalised patients with COVID-19 outside Wuhan
Intestinal Inflammation Modulates the Expression of ACE2 and TMPRSS2 and Potentially Overlaps With the Pathogenesis of SARS-CoV-2–related Disease
Association of Overlapped and Un-overlapped Comorbidities with COVID-19 Severity and Treatment Outcomes: A Retrospective Cohort Study from Nine Provinces in China.
Co-regulatory networks of human serum proteins link genetics to disease
EMT- and stroma-related gene expression and resistance to PD-1 blockade in urothelial cancer
Self-Recognition of an Inducible Host lncRNA by RIG-I Feedback Restricts Innate Immune Response
Oxidized phospholipids regulate amino acid metabolism through MTHFD2 to facilitate nucleotide release in endothelial cells
Multiscale network modeling of oligodendrocytes reveals molecular components of myelin dysregulation in Alzheimer’s disease
Gene expression elucidates functional impact of polygenic risk for schizophrenia
Variants in TRIM22 That Affect NOD2 Signaling Are Associated With Very-Early-Onset Inflammatory Bowel Disease
Functional Characterization of DNA Methylation in the Oligodendrocyte Lineage
Systems Nutrigenomics Reveals Brain Gene Networks Linking Metabolic and Brain Disorders
Gene Expression Elucidates Functional Impact of Polygenic Risk for Schizophrenia
Synchronized age-related gene expression changes across multiple tissues in human and the link to complex diseases
Molecular Portraits of Epithelial, Mesenchymal, and Hybrid States in Lung Adenocarcinoma and Their Relevance to Survival
Genome-wide CRISPR-Cas9 Screens Reveal Loss of Redundancy between PKMYT1 and WEE1 in Glioblastoma Stem-like Cells
Integrative network analysis reveals molecular mechanisms of blood pressure regulation
Integrative Analysis of DNA Methylation and Gene Expression Data Identifies EPAS1 as a Key Regulator of COPD
Targeting the SIN3A-PF1 interaction inhibits epithelial to mesenchymal transition and maintenance of a stem cell phenotype in triple negative breast cancer
Common dysregulation network in the human prefrontal cortex underlies two neurodegenerative diseases
Integrative Genomics Reveals Novel Molecular Pathways and Gene Networks for Coronary Artery Disease
Collaborative Research: RI: Medium: Understanding, Visualizing, and Attributing Multimodal Generative Models
CAREER: Exploiting Deep Generative Models for Visual Recognition
NSF/DMR-BSF: Quantum Transport in a Helical One-Dimensional System
Probing Charge, Spin and Thermoelectric Transport in Atomically Thin Materials
Convergent Research: NSF/DOE Quantum Science Summer School
Controlling Valley and Spin-Orbit Coupling in Graphene and Bilayer Graphene Nanostructures
CAREER: Mesoscopic Phenomena and Band-Structure Engineering in Single-Layer and Bilayer Graphene