Area of research
Pharmacology · Oncology
Research interest
Research interests include Drug, Transporter, Pharmacology, Physiologically based pharmacokinetic modelling, Pharmacokinetics, and Drug development.
Membrane transporters in drug development and as determinants of precision medicine
Clinical Implications of Altered Drug Transporter Abundance/Function and <scp>PBPK</scp> Modeling in Specific Populations: An <scp>ITC</scp> Perspective
Quantitative Translation of Microfluidic Transporter <i>in Vitro</i> Data to <i>in Vivo</i> Reveals Impaired Albumin-Facilitated Indoxyl Sulfate Secretion in Chronic Kidney Disease
Clinical Probes and Endogenous Biomarkers as Substrates for Transporter Drug‐Drug Interaction Evaluation: Perspectives From the International Transporter Consortium
Influence of Transporter Polymorphisms on Drug Disposition and Response: A Perspective From the International Transporter Consortium
The International Transporter Consortium: Summarizing Advances in the Role of Transporters in Drug Development
IMI – Oral biopharmaceutics tools project – Evaluation of bottom-up PBPK prediction success part 2: An introduction to the simulation exercise and overview of results
IMI – Oral biopharmaceutics tools project – Evaluation of bottom-up PBPK prediction success part 3: Identifying gaps in system parameters by analysing In Silico performance across different compound classes
PBPK models for the prediction of in vivo performance of oral dosage forms
Drug–Drug Interaction Potential of Marketed Oncology Drugs: In Vitro Assessment of Time-Dependent Cytochrome P450 Inhibition, Reactive Metabolite Formation and Drug–Drug Interaction Prediction