Area of research
Reproductive Medicine · Public Health, Environmental and Occupational Health
Research interest
Research interests include Biology, Flagellum, Male infertility, Genetics, Sperm, and Allele.
Co-exposure to 55 endocrine-disrupting chemicals linking diminished sperm quality: Mixture effect, and the role of seminal plasma docosapentaenoic acid
Multigenerational paternal obesity enhances the susceptibility to male subfertility in offspring via Wt1 N6-methyladenosine modification
Adenylate kinase phosphate energy shuttle underlies energetic communication in flagellar axonemes
Observed Effects on Very Early Pregnancy Linked to Ambient PM<sub>2.5</sub> Exposure in China among Women Undergoing <i>In Vitro</i> Fertilization-Embryo Transfer
Bi-allelic variants in chromatoid body protein TDRD6 cause spermiogenesis defects and severe oligoasthenoteratozoospermia in humans
Deficiency of MFSD6L, an acrosome membrane protein, causes oligoasthenoteratozoospermia in humans and mice
CALR3 defects disrupt sperm-zona pellucida binding in humans: new insights into male factor fertilization failure and relevant clinical therapeutic approaches
Association of novel DNAH11 variants with asthenoteratozoospermia lead to male infertility
ACROSIN deficiency causes total fertilization failure in humans by preventing the sperm from penetrating the zona pellucida
Biallelic mutations in <i>CFAP54</i> cause male infertility with severe MMAF and NOA
Deficiency of primate-specific SSX1 induced asthenoteratozoospermia in infertile men and cynomolgus monkey and tree shrew models
Bi-allelic human<i>TEKT3</i>mutations cause male infertility with oligoasthenoteratozoospermia owing to acrosomal hypoplasia and reduced progressive motility
Novel deleterious splicing variant in HFM1 causes gametogenesis defect and recurrent implantation failure: concerning the risk of chromosomal abnormalities in embryos
Prioritizing de novo potential non-canonical splicing variants in neurodevelopmental disorders
Novel <scp> <i>MEIOB</i> </scp> pathogenic variants including a homozygous non‐canonical splicing variant, cause meiotic arrest and human non‐obstructive azoospermia
Activation of MT1/MT2 to Protect Testes and Leydig Cells against Cisplatin-Induced Oxidative Stress through the SIRT1/Nrf2 Signaling Pathway
Identification of deleterious variants in patients with male infertility due to idiopathic non-obstructive azoospermia
Loss of function mutation in <i>DNAH7</i> induces male infertility associated with abnormalities of the sperm flagella and mitochondria in human
Deficiency of X-linked TENT5D causes male infertility by disrupting the mRNA stability during spermatogenesis
Homozygous SPAG6 variants can induce nonsyndromic asthenoteratozoospermia with severe MMAF
Homozygous missense mutation in CCDC155 disrupts the transmembrane distribution of CCDC155 and SUN1, resulting in non-obstructive azoospermia and premature ovarian insufficiency in humans
Performance evaluation of differential splicing analysis methods and splicing analytics platform construction
Novel <i>FSIP2</i> Variants Induce Super-Length Mitochondrial Sheath and Asthenoteratozoospermia in Humans
Homozygous variants in <i>AKAP3</i> induce asthenoteratozoospermia and male infertility
Biallelic loss‐of‐function mutations in <i>SEPTIN4</i> ( <i>C17ORF47</i> ), encoding a conserved annulus protein, cause thin midpiece spermatozoa and male infertility in humans
Deleterious variants in X-linked CFAP47 induce asthenoteratozoospermia and primary male infertility
Bi-allelic mutations of DNAH10 cause primary male infertility with asthenoteratozoospermia in humans and mice
Loss of DRC1 function leads to multiple morphological abnormalities of the sperm flagella and male infertility in human and mouse
Novel bi-allelic variants in DNAH2 cause severe asthenoteratozoospermia with multiple morphological abnormalities of the flagella
Bi-allelic variants in DNHD1 cause flagellar axoneme defects and asthenoteratozoospermia in humans and mice