Area of research
Molecular Biology · Cell Biology
Research interest
Research interests include Pluripotent Stem Cells Research, CRISPR and Genetic Engineering, Zebrafish Biomedical Research Applications, and Chronic Myeloid Leukemia Treatments.
Design of soluble Notch agonists that drive T cell development and boost immunity
The dynamics of hematopoiesis over the human lifespan
Maturation and persistence of CAR T cells derived from human pluripotent stem cells via chemical inhibition of G9a/GLP
Dynamic nucleolar phase separation influenced by non-canonical function of LIN28A instructs pluripotent stem cell fate decisions
Generation of Functional iPSC-Derived CAR-T Cells for Cancer Immunotherapy Via G9a/GLP Inhibition
In Vivo Reprogramming of Adult Liver Sinusoidal Vascular Endothelial Cells into a Hematopoietic Stem and Progenitor Cell Niche
EZH1 repression generates mature iPSC-derived CAR T cells with enhanced antitumor activity
CellComm infers cellular crosstalk that drives haematopoietic stem and progenitor cell development
Developmental maturation of the hematopoietic system controlled by a Lin28b-let-7-Cbx2 axis
Hypoxic, glycolytic metabolism is a vulnerability of B-acute lymphoblastic leukemia-initiating cells
ISSCR Guidelines for Stem Cell Research and Clinical Translation: The 2021 update
Evidence generation and reproducibility in cell and gene therapy research: A call to action
SARS-CoV-2 viral load is associated with increased disease severity and mortality
The Toughest Triage — Allocating Ventilators in a Pandemic
Pancreatic circulating tumor cell profiling identifies LIN28B as a metastasis driver and drug target
LIN28B regulates transcription and potentiates MYCN-induced neuroblastoma through binding to ZNF143 at target gene promotors
Diversification of reprogramming trajectories revealed by parallel single-cell transcriptome and chromatin accessibility sequencing
Mitochondrial and Redox Modifications in Huntington Disease Induced Pluripotent Stem Cells Rescued by CRISPR/Cas9 CAGs Targeting
Calmodulin inhibitors improve erythropoiesis in Diamond-Blackfan anemia
Transcriptome Dynamics of Hematopoietic Stem Cell Formation Revealed Using a Combinatorial Runx1 and Ly6a Reporter System
3126 – SINGLE CELL SEQUENCING OF MLL-REARRANGED LEUKEMIA REVEALS MECHANISMS OF LEUKEMIA INITIATING CELL PLASTICITY
Induced pluripotent stem cells in disease modelling and drug discovery
Stem Cells in the Treatment of Disease
The Lin28/let-7 Pathway Regulates the Mammalian Caudal Body Axis Elongation Program
Author Correction: Epoxyeicosatrienoic acids enhance embryonic haematopoiesis and adult marrow engraftment
Small-Molecule Inhibitors Disrupt let-7 Oligouridylation and Release the Selective Blockade of let-7 Processing by LIN28
Reconstruction of complex single-cell trajectories using CellRouter
Regulation of embryonic haematopoietic multipotency by EZH1
Building Capacity for a Global Genome Editing Observatory: Institutional Design
Building Capacity for a Global Genome Editing Observatory: Conceptual Challenges