Area of research
Pulmonary and Respiratory Medicine · Genetics
Research interest
Research interests include Advanced Breast Cancer Therapies, Estrogen and related hormone effects, Cancer Cells and Metastasis, and Cancer Genomics and Diagnostics.
Spatiotemporal dynamics of tumor microenvironment remodeling
International multidisciplinary consensus on the integration of radiotherapy with new systemic treatments for breast cancer: European Society for Radiotherapy and Oncology (ESTRO)-endorsed recommendations
Netrin-1 blockade inhibits tumor associated Myeloid-derived suppressor cells, cancer stemness and alleviates resistance to chemotherapy and immune checkpoint inhibitor
Essential requirements for reporting radiation therapy in breast cancer clinical trials: An international multi-disciplinary consensus endorsed by the European Society for Radiotherapy and Oncology (ESTRO)
Nuclear PRMT5 is a biomarker of sensitivity to tamoxifen in ERα+ breast cancer
Original dataset from Ants act as olfactory bio-detectors of tumours in patient-derived xenograft mice
Identifying biomarkers of differential chemotherapy response in TNBC patient-derived xenografts with a CTD/WGCNA approach
Abstract PD9-07: Mdm2 gene amplification in estrogen receptor-positive breast cancer cells is associated with enhanced solid tumor growth and pronounced metastatic potential in humanized tumor mice (HTM) and a poor outcome of patients with luminal breast cancer
Eine mdm2 Genamplifikation ist mit Progression und Metastasierung desluminalen Mammakarzinoms im humanisierten Tumormausmodell (hPDX) assoziiert,sowie mit einem ungünstigen klinischen Verlauf derErkrankung
Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts
YAP and β-Catenin Cooperate to Drive Oncogenesis in Basal Breast Cancer
<i>mdm2</i> gene amplification is associated with luminal breast cancer progression in humanized <scp>PDX</scp> mice and a worse outcome of estrogen receptor positive disease
Enhancer reprogramming driven by high-order assemblies of transcription factors promotes phenotypic plasticity and breast cancer endocrine resistance
Tumour kinome re-wiring governs resistance to palbociclib in oestrogen receptor positive breast cancers, highlighting new therapeutic modalities
Abstract 1685: The EurOPDX Research Infrastructure: Supporting European and worldwide cancer research with patient-derived xenografts
Reprogramming of Amino Acid Transporters to Support Aspartate and Glutamate Dependency Sustains Endocrine Resistance in Breast Cancer
The arginine methyltransferase PRMT1 regulates IGF-1 signaling in breast cancer
Oestrogen Non-Genomic Signalling is Activated in Tamoxifen-Resistant Breast Cancer
Interrogating open issues in cancer precision medicine with patient-derived xenografts
A Biobank of Breast Cancer Explants with Preserved Intra-tumor Heterogeneity to Screen Anticancer Compounds
Patient-derived xenograft (PDX) models in basic and translational breast cancer research
The molecular mechanisms underlying the ERα-36-mediated signaling in breast cancer
Diaphragmatic ultrasonography during spontaneous breathing trials in critically ill patients: Can it identify weaning failure?
Activation of IFN/STAT1 signalling predicts response to chemotherapy in oestrogen receptor-negative breast cancer
Endobronchial Metastases of Renal Cell Carcinoma: A Complex Multidisciplinary Treatment
Polymer coating of carrier excipients modify aerosol performance of adhered drugs used in dry powder inhalation therapy