Area of research
Molecular Biology · Genetics
Research interest
Research interests include Single-cell and spatial transcriptomics, RNA and protein synthesis mechanisms, Bacterial Genetics and Biotechnology, and Gene expression and cancer classification.
Proteome-wide determinants of co-translational chaperone binding in bacteria
MOFA-FLEX: A Factor Model Framework for Integrating Omics Data with Prior Knowledge
SpatialData: an open and universal data framework for spatial omics
Spatio-temporal transcriptomics of chromothriptic SHH-medulloblastoma identifies multiple genetic clones that resist treatment and drive relapse
The scverse project provides a computational ecosystem for single-cell omics data analysis
Spatial multiomics map of trophoblast development in early pregnancy
Multiplexed protein stability (MPS) profiling of terminal degrons using fluorescent timer libraries in Saccharomyces cerevisiae
Spatial and temporal transcriptomics of SHH-medulloblastoma with chromothripsis identifies multiple genetic clones that resist to treatment and lead to relapse
MUON: multimodal omics analysis framework
Spatially resolved single-cell multiomics map of human trophoblast differentiation in early pregnancy
SpatialDE2: Fast and localized variance component analysis of spatial transcriptomics
Timer-based proteomic profiling of the ubiquitin-proteasome system reveals a substrate receptor of the GID ubiquitin ligase
Up-regulation of ubiquitin–proteasome activity upon loss of NatA-dependent N-terminal acetylation
Muon: multimodal omics analysis framework
Mechanisms of up-regulation of Ubiquitin-Proteasome activity in the absence of NatA dependent N-terminal acetylation
Translational Regulation of Pmt1 and Pmt2 by Bfr1 Affects Unfolded Protein O-Mannosylation
Translational regulation of Pmt1 and Pmt2 by Bfr1 affects unfolded protein O-mannosylation
Mapping Degradation Signals and Pathways in a Eukaryotic N-terminome
Genome-wide C-SWAT library for high-throughput yeast genome tagging
Bicoid gradient formation mechanism and dynamics revealed by protein lifetime analysis
Bicoid gradient formation mechanism and dynamics revealed by protein lifetime analysis
Upregulation of SPS100 gene expression by an antisense RNA via a switch of mRNA isoforms with different stabilities
A genome-wide resource for high-throughput genomic tagging of yeast ORFs
Live-cell multiphoton fluorescence correlation spectroscopy with an improved large Stokes shift fluorescent protein
Creating functional engineered variants of the single-module non-ribosomal peptide synthetase IndC by T domain exchange