Area of research
Molecular Biology
Research interest
Research interests include Biology, Computational biology, Gene, Cilium, Ciliopathies, and Cell biology.
Functional characterization of a human epilepsy-associated gene network reveals metabolic regulation as a critical factor underlying seizure susceptibilities
Structural basis of LRPPRC–SLIRP-dependent translation by the mitoribosome
Antiviral responses induced by Tdap-IPV vaccination are associated with persistent humoral immunity to Bordetella pertussis
SARS-CoV-2 mucosal antibody development and persistence and their relation to viral load and COVID-19 symptoms
A Prioritized and Validated Resource of Mitochondrial Proteins in <i>Plasmodium</i> Identifies Unique Biology
Novel high-resolution targeted sequencing of the cervicovaginal microbiome
TMEM70 functions in the assembly of complexes I and V
Metabolic models predict bacterial passengers in colorectal cancer
CiliaCarta: An integrated and validated compendium of ciliary genes
Diabetes is associated with genotypically drug-resistant tuberculosis
Towards predicting the environmental metabolome from metagenomics with a mechanistic model
Probabilistic data integration identifies reliable gametocyte-specific proteins and transcripts in malaria parasites
Mammalian embryo comparison identifies novel pluripotency genes associated with the naïve or primed state
Large-scale genomic analysis shows association between homoplastic genetic variation in Mycobacterium tuberculosis genes and meningeal or pulmonary tuberculosis
Modest heterologous protection after Plasmodium falciparum sporozoite immunization: a double-blind randomized controlled clinical trial
An organelle-specific protein landscape identifies novel diseases and molecular mechanisms
ATP6AP1 deficiency causes an immunodeficiency with hepatopathy, cognitive impairment and abnormal protein glycosylation
CCDC115 Deficiency Causes a Disorder of Golgi Homeostasis with Abnormal Protein Glycosylation
TMEM199 Deficiency Is a Disorder of Golgi Homeostasis Characterized by Elevated Aminotransferases, Alkaline Phosphatase, and Cholesterol and Abnormal Glycosylation
Proteomics of Human Dendritic Cell Subsets Reveals Subset-Specific Surface Markers and Differential Inflammasome Function
An siRNA-based functional genomics screen for the identification of regulators of ciliogenesis and ciliopathy genes
Evolution and structural organization of the mitochondrial contact site (MICOS) complex and the mitochondrial intermembrane space bridging (MIB) complex
Integrative Genomics-Based Discovery of Novel Regulators of the Innate Antiviral Response
Sequence specificity between interacting and non-interacting homologs identifies interface residues – a homodimer and monomer use case
A mutation in the human CBP4 ortholog UQCC3 impairs complex III assembly, activity and cytochrome b stability
The SYSCILIA gold standard (SCGSv1) of known ciliary components and its applications within a systems biology consortium
Evolution of modular intraflagellar transport from a coatomer-like progenitor
Mutations in the UQCC1-Interacting Protein, UQCC2, Cause Human Complex III Deficiency Associated with Perturbed Cytochrome b Protein Expression
Human Intellectual Disability Genes Form Conserved Functional Modules in Drosophila
Iterative orthology prediction uncovers new mitochondrial proteins and identifies C12orf62 as the human ortholog of COX14, a protein involved in the assembly of cytochrome coxidase