Area of research
Molecular Biology · Cancer Research
Research interest
Research interests include Melanoma and MAPK Pathways, Cancer Genomics and Diagnostics, Protein Kinase Regulation and GTPase Signaling, and Cutaneous Melanoma Detection and Management.
SOX2 confers tumour permissiveness in a specific skin progenitor population.
Use of circulating tumour DNA to prospectively guide a switch from targeted to immune therapy in BRAF mutant advanced melanoma: the randomised phase II CAcTUS trial
SOX2 empowers a rapid tumorigenic programme from the tumour-resistant population in the skin
Longitudinal gut microbiome changes in immune checkpoint blockade-treated advanced melanoma
The journey from melanocytes to melanoma.
Functional classification of DDOST variants of uncertain clinical significance in congenital disorders of glycosylation.
Cross-cohort gut microbiome associations with immune checkpoint inhibitor response in advanced melanoma
MiR-378a inhibits glucose metabolism by suppressing GLUT1 in prostate cancer.
Cost-effectiveness of a policy-based intervention to reduce melanoma and other skin cancers associated with indoor tanning.
Melanoma models for the next generation of therapies
The T cell receptor repertoire of tumor infiltrating T cells is predictive and prognostic for cancer survival.
Ultraviolet radiation drives mutations in a subset of mucosal melanomas.
Molecular characterization of fast-growing melanomas
Sunglasses to hide behind may also prevent melanoma of the eyes.
Map3k1 Loss Cooperates with Braf<sup>V600E</sup> to Drive Melanomagenesis.
Author Correction: The T cell receptor repertoire of tumor infiltrating T cells is predictive and prognostic for cancer survival.
MOLECULAR LANDSCAPE OF OLD AGE MELANOMA BY SURVIVAL AND IMMUNOTHERAPY RESPONSE
Immune awakening revealed by peripheral T cell dynamics after one cycle of immunotherapy
Immune-awakening revealed by peripheral T cell dynamics after one cycle of immunotherapy.
Stroma remodeling and reduced cell division define durable response to PD-1 blockade in melanoma.
Brain microenvironment-driven resistance to immune and targeted therapies in acral melanoma
Utility of ctDNA to support patient selection for early phase clinical trials: the TARGET study.
Ultraviolet radiation-induced DNA damage is prognostic for outcome in melanoma.
So Close, yet so Far: Discrepancies between Uveal and Other Melanomas. A Position Paper from UM Cure 2020.
A PAX3/BRN2 rheostat controls the dynamics of BRAF mediated MITF regulation in MITF<sup>high</sup> /AXL<sup>low</sup> melanoma.
Publisher Correction: Ultraviolet radiation-induced DNA damage is prognostic for outcome in melanoma.
Abstract 3994: Genomic characterization of melanoma in the elderly reveals molecular drivers of progression and prognosis associated with immunotherapy response
Age Correlates with Response to Anti-PD1, Reflecting Age-Related Differences in Intratumoral Effector and Regulatory T-Cell Populations
MAPK pathway activation in the embryonic pituitary results in stem cell compartment expansion, differentiation defects and provides insights into the pathogenesis of papillary craniopharyngioma
Consensus on precision medicine for metastatic cancers: a report from the MAP conference