Area of research
Molecular Biology · Biochemistry
Research interest
Research interests include Connexins and lens biology, Sulfur Compounds in Biology, Retinal Diseases and Treatments, and Retinal Development and Disorders.
Persistence of vascular empty sleeves in choroidal neovascularization after VEGF therapy in both animal models and humans.
Mechanisms of RPE senescence and potential role of αB crystallin peptide as a senolytic agent in experimental AMD.
Oxidative Stress and Lipid Accumulation Augments Cell Death in LDLR-Deficient RPE Cells and Ldlr−/− Mice
Glutathione Metabolism and the Novel Role of Mitochondrial GSH in Retinal Degeneration
Mechanisms of mitochondrial dysfunction and their impact on age-related macular degeneration
The Emerging Role of Senescence in Ocular Disease.
Mechanisms of protection of retinal pigment epithelial cells from oxidant injury by humanin and other mitochondrial-derived peptides: Implications for age-related macular degeneration.
The humanin peptide mediates ELP nanoassembly and protects human retinal pigment epithelial cells from oxidative stress.
Transporter-Mediated Mitochondrial GSH Depletion Leading to Mitochondrial Dysfunction and Rescue with αB Crystallin Peptide in RPE Cells.
Loss of NRF-2 and PGC-1α genes leads to retinal pigment epithelium damage resembling dry age-related macular degeneration.
The Regulation of NFE2L2 (NRF2) Signalling and Epithelial-to-Mesenchymal Transition in Age-Related Macular Degeneration Pathology.
Characterization and Regulation of Carrier Proteins of Mitochondrial Glutathione Uptake in Human Retinal Pigment Epithelium Cells.
A Novel HDL-Mimetic Peptide HM-10/10 Protects RPE and Photoreceptors in Murine Models of Retinal Degeneration.
Loss of NRF-2 and PGC-1α genes leads to retinal pigment epithelium damage resembling dry age-related macular degeneration
Telomerase RNA biogenesis involves sequential binding by Sm and Lsm complexes