Area of research
Molecular Biology · Genetics
Research interest
Research interests include Inflammasome and immune disorders, Glioma Diagnosis and Treatment, Meningioma and schwannoma management, and Brain Metastases and Treatment.
Stereotactic radiosurgery for patients with brain metastases: current principles, expanding indications and opportunities for multidisciplinary care
Characterization of Genetic Landscape and Novel Inflammatory Biomarkers in Patients With Adult-Onset Still's Disease.
FACS-based detection of extracellular ASC specks from NLRP3 inflammasomes in inflammatory diseases.
Elevated serum levels of interleukin-18 discriminate Still's disease from other autoinflammatory conditions: results from the European ImmunAID cohort.
Quantitative AI yields algorithmic RNA biomarkers from a rheumatoid arthritis clinical trial, accurately predicting individual patient responses to anti-TNF treatment, providing a novel approach to companion diagnostic discovery.
Distinct Natural Killer Cell Signature in Still Disease: Insights From a Multinational Immunome Project Consortium for Autoinflammatory Disorders.
The Miami Framework for ALS and related neurodegenerative disorders: an integrated view of phenotype and biology
Inflammatory profile of lower risk myelodysplastic syndromes.
Novel Targeted Therapies for Rheumatoid Arthritis Based on Intracellular Signalling and Immunometabolic Changes: A Narrative Review.
A nosology of immune diseases from deep immunophenotyping.
Interactive Effects of Molecular, Therapeutic, and Patient Factors on Outcome of Diffuse Low-Grade Glioma
Safety and efficacy of arimoclomol for inclusion body myositis: a multicentre, randomised, double-blind, placebo-controlled trial
Recovery of Bone Marrow Function in VEXAS Syndrome-potential Role for Romiplostim.
Inhibition of IRE1 RNase activity modulates tumor cell progression and enhances the response to chemotherapy in colorectal cancer.
Faculty Opinions recommendation of CCR7 acts as both a sensor and a sink for CCL19 to coordinate collective leukocyte migration.
Faculty Opinions recommendation of Drivers of heterogeneity in synovial fibroblasts in rheumatoid arthritis.
Faculty Opinions recommendation of A subset of antibodies targeting citrullinated proteins confers protection from rheumatoid arthritis.
Faculty Opinions recommendation of Itaconate ameliorates autoimmunity by modulating T cell imbalance via metabolic and epigenetic reprogramming.
Effect of Different Corticosteroid Dosing Regimens on Clinical Outcomes in Boys With Duchenne Muscular Dystrophy
Interferon-α-mediated therapeutic resistance in early rheumatoid arthritis implicates epigenetic reprogramming.
Steroid hormone catabolites activate the pyrin inflammasome through a non-canonical mechanism
Inflammasome activation: from molecular mechanisms to autoinflammation.
Steroid hormone catabolites activate the pyrin inflammasome through a non-canonical mechanism.
RA-MAP, molecular immunological landscapes in early rheumatoid arthritis and healthy vaccine recipients.
An Atypical Autoinflammatory Disease Due to an LRR Domain NLRP3 Mutation Enhancing Binding to NEK7.
Functional outcome measures in young, steroid-naïve boys with Duchenne muscular dystrophy
Faculty Opinions recommendation of Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages.
Faculty Opinions recommendation of Investigation of genetically regulated gene expression and response to treatment in rheumatoid arthritis highlights an association between IL18RAP expression and treatment response.
Faculty Opinions recommendation of CD4+ memory stem T cells recognizing citrullinated epitopes are expanded in patients with rheumatoid arthritis and sensitive to tumor necrosis factor blockade.
Faculty Opinions recommendation of Changes in plasma itaconate elevation in early rheumatoid arthritis patients elucidates disease activity associated macrophage activation.