Area of research
Genetics · Pulmonary and Respiratory Medicine
Research interest
Research interests include Breast cancer, Biology, Cell biology, Fulvestrant, Oncology, and Stem cell.
Abstract PS1-12-11: Giredestrant immobilizes the Estrogen Receptor to potently suppress ER-active breast cancers
Preclinical models of breast cancer metastasis: strengths, limitations, and clinical relevance
Loss of luminal lineage drives resistance to next-generation ERα antagonists in pretreated ER+ HER2− locally-advanced or metastatic breast cancer
Epiregulon: Single-cell transcription factor activity inference to predict drug response and drivers of cell states
Transformer-based modeling of Clonal Selection and Expression Dynamics reveals resistance mechanisms in breast cancer
Clinical Context Shapes the Relationship between Genomic Alterations and Response to AR Inhibitors and Chemotherapy in Metastatic Prostate Cancer
CDK4/6i-treated HR+/HER2- breast cancer tumors show higher ESR1 mutation prevalence and more altered genomic landscape
Transformer-based modeling of Clonal Selection and Expression Dynamics (TraCSED) reveals resistance signatures in breast cancer
Notch signaling maintains a progenitor-like subclass of hepatocellular carcinoma
Disruption of stem cell niche–confined R-spondin 3 expression leads to impaired hematopoiesis
Discovery of GNE-502 as an orally bioavailable and potent degrader for estrogen receptor positive breast cancer
Therapeutic Ligands Antagonize Estrogen Receptor Function by Impairing Its Mobility
The Hedgehog Hold on Homeostasis
Lgr5+ Stem Cells Are Indispensable for Radiation-Induced Intestinal Regeneration