Area of research
Genetics · Immunology
Research interest
Research interests include Inflammatory Bowel Disease, T-cell and B-cell Immunology, Genetic Associations and Epidemiology, and Helicobacter pylori-related gastroenterology studies.
Postoperative Ileum Transcriptomics Implicate Sex-Biased Mechanisms in Crohn’s Disease Recurrence
Comprehensive Association Analyses of Extraintestinal Manifestations in Inflammatory Bowel Disease
Challenges in IBD Research 2024: Precision Medicine
Eleven Grand Challenges for Inflammatory Bowel Disease Genetics and Genomics
Genetic architecture of the inflammatory bowel diseases across East Asian and European ancestries
Serum Lipidomic Screen Identifies Key Metabolites, Pathways, and Disease Classifiers in Crohn’s Disease
Clinical Predictors of Early and Late Endoscopic Recurrence Following Ileocolonic Resection in Crohn’s Disease
Genetic coding variant in complement factor B (CFB) is associated with increased risk for perianal Crohn’s disease and leads to impaired CFB cleavage and phagocytosis
Identifying high-impact variants and genes in exomes of Ashkenazi Jewish inflammatory bowel disease patients
Human enteric viruses autonomously shape inflammatory bowel disease phenotype through divergent innate immunomodulation
Inflamed Ulcerative Colitis Regions Associated With MRGPRX2-Mediated Mast Cell Degranulation and Cell Activation Modules, Defining a New Therapeutic Target
Whole-genome sequencing of African Americans implicates differential genetic architecture in inflammatory bowel disease
Transethnic analysis of the human leukocyte antigen region for ulcerative colitis reveals not only shared but also ethnicity-specific disease associations
A Role for CXCR3 Ligands as Biomarkers of Post-Operative Crohn’s Disease Recurrence
Serum Analyte Profiles Associated With Crohn’s Disease and Disease Location
Common and Rare Variant Prediction and Penetrance of IBD in a Large, Multi-ethnic, Health System-based Biobank Cohort
Comparative performances of machine learning methods for classifying Crohn Disease patients using genome-wide genotyping data
Functional variants in the <i>LRRK2</i> gene confer shared effects on risk for Crohn’s disease and Parkinson’s disease
<i>C1orf106</i> is a colitis risk gene that regulates stability of epithelial adherens junctions
Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population
A comprehensive evaluation of the genetic architecture of sudden cardiac arrest
Fine-mapping inflammatory bowel disease loci to single-variant resolution
Transancestral mapping and genetic load in systemic lupus erythematosus
Genetic Factors Interact With Tobacco Smoke to Modify Risk for Inflammatory Bowel Disease in Humans and Mice
Genome-Wide Association Study Identifies African-Specific Susceptibility Loci in African Americans With Inflammatory Bowel Disease
A Pleiotropic Missense Variant in SLC39A8 Is Associated With Crohn’s Disease and Human Gut Microbiome Composition
Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals
Appendectomy does not decrease the risk of future colectomy in UC: results from a large cohort and meta-analysis
A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis
Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus