Area of research
Immunology · Physiology
Research interest
Research interests include T-cell and B-cell Immunology, Calcium signaling and nucleotide metabolism, Immune Cell Function and Interaction, and Immunotherapy and Immune Responses.
A roadmap for defining “extrafollicular” B cell responses
Transcription factor T-bet regulates the maintenance and differentiation potential of lymph node and lung effector memory B cell subsets
Intranasal replicon SARS-CoV-2 vaccine produces protective respiratory and systemic immunity and prevents viral transmission
Topography of the HLA-A protein enforces shared and convergent immunodominant B cell and antibody alloresponses in transplant recipients
CD38 promotes hematopoietic stem cell dormancy
The Marginal Zone B Cell Compartment and T Cell–independent Antibody Responses Are Supported by B Cell Intrinsic Expression of IRF1
A transcriptionally distinct subset of influenza-specific effector memory B cells predicts long-lived antibody responses to vaccination in humans
Activation of regulatory dendritic cells by Mertk coincides with a temporal wave of apoptosis in neonatal lungs
GABA and Combined GABA with GAD65-Alum Treatment Alters Th1 Cytokine Responses of PBMCs from Children with Recent-Onset Type 1 Diabetes
CD38 promotes hematopoietic stem cell dormancy via c-Fos
A nonredundant role for T cell-derived interleukin 22 in antibacterial defense of colonic crypts
A single intranasal administration of AdCOVID protects against SARS-CoV-2 infection in the upper and lower respiratory tracts
Single-Dose Intranasal Administration of AdCOVID Elicits Systemic and Mucosal Immunity against SARS-CoV-2 and Fully Protects Mice from Lethal Challenge
IFNγ induces epigenetic programming of human T-bethi B cells and promotes TLR7/8 and IL-21 induced differentiation
T-bet Transcription Factor Promotes Antibody-Secreting Cell Differentiation by Limiting the Inflammatory Effects of IFN-γ on B Cells
Compartmentalization of dendritic cell and T‐cell interactions in the lymph node: Anatomy of T‐cell fate decisions
Complexity and heterogeneity – the defining features of autoimmune disease
Distinct Effector B Cells Induced by Unregulated Toll-like Receptor 7 Contribute to Pathogenic Responses in Systemic Lupus Erythematosus
The establishment of resident memory B cells in the lung requires local antigen encounter
Human Leukocyte Antigen Class I and II Knockout Human Induced Pluripotent Stem Cell–Derived Cells: Universal Donor for Cell Therapy
Factors of the bone marrow microniche that support human plasma cell survival and immunoglobulin secretion
Dynamic regulation of T follicular regulatory cell responses by interleukin 2 during influenza infection
Blimp-1–dependent and –independent natural antibody production by B-1 and B-1–derived plasma cells
CD38 knockout suppresses tumorigenesis in mice and clonogenic growth of human lung cancer cells
T Follicular Helper Cell Plasticity Shapes Pathogenic T Helper 2 Cell-Mediated Immunity to Inhaled House Dust Mite
CD38 in the pathogenesis of allergic airway disease: Potential therapeutic targets
Alzheimer's disease pathology is attenuated in a <scp>CD</scp>38‐deficient mouse model
B Lymphocytes Are Required during the Early Priming of CD4+ T Cells for Clearance of <i>Pneumocystis</i> Infection in Mice
Discovery of Potent Inhibitors of <i>Schistosoma mansoni</i> NAD<sup>+</sup> Catabolizing Enzyme
Airway responsiveness in CD38-deficient mice in allergic airway disease: studies with bone marrow chimeras
Evolution and Durability of Human T and B Cell Responses
Core A: Administrative Core
Project 1: Evolution and Durability of allo(auto)immune B cell responses in organ transplant recipients
Identification and characterization of effector memory B cell populations that dominate memory responses to subsequent influenza infection and vaccination
Identification and characterization of effector memory B cell populations that dominate memory responses to subsequent influenza infection and vaccination
Identification and characterization of effector memory B cell populations that dominate memory responses to subsequent influenza infection and vaccination
TLR7 and TLR9-directed plasma cell formation: Dissecting the molecular basis for their differential dependence on IFN-induced signals
Identification and characterization of effector memory B cell populations that dominate memory responses to subsequent influenza infection and vaccination
TLR7 and TLR9-directed plasma cell formation: Dissecting the molecular basis for their differential dependence on IFN-induced signals
TLR7 and TLR9-directed plasma cell formation: Dissecting the molecular basis for their differential dependence on IFN-induced signals
TLR7 and TLR9-directed plasma cell formation: Dissecting the molecular basis for their differential dependence on IFN-induced signals
TLR7 and TLR9-directed plasma cell formation: Dissecting the molecular basis for their differential dependence on IFN-induced signals
Tissue and organ specific human B cell immunity
Characterization of virus-specific human B cell subsets in lymphoid and non-lymphoid tissues
Tissue and organ specific human B cell immunity
Tissue and organ specific human B cell immunity
Tissue and organ specific human B cell immunity
Tissue and organ specific human B cell immunity: Supplement - Metabolic Risk Factors and Inflammation in PASC Development
Characterization of virus-specific human B cell subsets in lymphoid and non-lymphoid tissues
Control of antiviral-viral B cell responses by IFNy T-bet and Eomes
Regulation of T cell responses to allergens and environmental microbes
Control of B cell differentiation by IFNg induced transcription factors
Control of B cell differentiation by IFNg induced transcription factors
Control of B cell differentiation by IFNg induced transcription factors