Area of research
Molecular Biology · Cancer Research
Research interest
Research interests include DNA Repair Mechanisms, RNA modifications and cancer, MicroRNA in disease regulation, and Epigenetics and DNA Methylation.
Metformin counteracts lipid accumulation and cell proliferation in hepatocellular carcinoma via regulating METTL3-mediated m<sup>6</sup>A methylation.
m6A methyltransferase METTL3 promotes non-small-cell lung carcinoma progression by inhibiting the RIG-I-MAVS innate immune pathway.
The methyltransferase METTL3 promotes the progression of breast cancer cells via regulating EGF m6A modification.
PCAF-mediated acetylation regulates RAD51 dynamic localization on chromatin during HR repair.
APE1 inhibition enhances ferroptotic cell death and contributes to hepatocellular carcinoma therapy.
The 8-oxoguanine DNA glycosylase-synaptotagmin 7 pathway increases extracellular vesicle release and promotes tumour metastasis during oxidative stress.
Establishment and external validation of prognosis prediction nomogram for patients with distant metastatic intrahepatic cholangiocarcinoma: based on a large population
MicroRNA regulation of adrenal glucocorticoid and androgen biosynthesis.
Correction: DNA polymerase beta modulates cancer progression via enhancing CDH13 expression by promoter demethylation.
Anti-mesothelin CAR-T immunotherapy in patients with ovarian cancer.
Hepatocytic lipocalin-2 controls HDL metabolism and atherosclerosis via Nedd4-1-SR-BI axis in mice.
Imaging and detection of sulfite in acute liver injury with a novel quinoxaline-based fluorescent probe
Self-delivery of TIGIT-blocking scFv enhances CAR-T immunotherapy in solid tumors.
Rabies virus glycoprotein 29 (RVG29) promotes CAR-T immunotherapy for glioma.
GAPDH facilitates homologous recombination repair by stabilizing RAD51 in an HDAC1-dependent manner.
Excessive iron inhibits insulin secretion via perturbing transcriptional regulation of SYT7 by OGG1.
RNA G-Quadruplex within the 5'-UTR of FEN1 Regulates mRNA Stability under Oxidative Stress.
Targeting CD24 in Cancer Immunotherapy.
Inhibition of FEN1 promotes DNA damage and enhances chemotherapeutic response in prostate cancer cells.
Impeding DNA Polymerase β Activity by Oleic Acid to Inhibit Base Excision Repair and Induce Mitochondrial Dysfunction in Hepatic Cells.
Netrin-1: An emerging player in inflammatory diseases
METTL3 promotes homologous recombination repair and modulates chemotherapeutic response in breast cancer by regulating the EGF/RAD51 axis.
Small-Molecule Inhibitors Targeting FEN1 for Cancer Therapy.
A novel mechanism for macrophage pyroptosis in rheumatoid arthritis induced by Pol β deficiency.
METTL3 antagonizes 5‑FU chemotherapy and confers drug resistance in colorectal carcinoma.
Validating RRP12 Expression and Its Prognostic Significance in HCC Based on Data Mining and Bioinformatics Methods
Inhibition of O-GlcNAc transferase sensitizes prostate cancer cells to docetaxel.
Genipin improves lipid metabolism and sperm parametersin obese mice via regulation of miR-132 expression.
FEN1 inhibitor synergizes with low-dose camptothecin to induce increased cell killing via the mitochondria mediated apoptotic pathway.
Analysis of N <sup>6</sup> -methyladenosine RNA Modification Levels by Dot Blotting.