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Siwen Hu‐Lieskovan

University of Utah Health Care · US
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Area of research
Oncology · Immunology
Research interest
Research interests include Cancer Immunotherapy and Biomarkers, CAR-T cell therapy research, Immunotherapy and Immune Responses, and Immune Cell Function and Interaction.
h-index
48
citations
24,973
works
292
NIH funding
primary concept
Medicine
email

Recent publications

Genetic Drivers of Sensitivity or Resistance to RAS(ON) Multi-Selective Inhibitors in NRAS-Mutated Melanoma
Cancer Research 2026cited by 0position: contributordoi
Cellular neighborhoods govern antitumor T-cell infiltration following anti-CTLA-4 in melanoma with primary resistance to anti-PD-1.
2026cited by 0position: contributordoi
SUPRAME: A phase 3 trial comparing IMA203, an engineered T-cell receptor expressing T cell therapy (TCR-T) vs investigator’s choice in patients with previously treated advanced cutaneous melanoma.
Journal of Clinical Oncology 2025cited by 2position: middledoi
Human Immunodeficiency Virus-Associated Differences in the Tumor Immune Microenvironment of Lung, Breast, and Prostate Cancers.
2025cited by 0position: contributordoi
Data from Human Immunodeficiency Virus–Associated Differences in the Tumor Immune Microenvironment of Lung, Breast, and Prostate Cancers
2025cited by 0position: contributordoi
Supplemental Table 1 from Human Immunodeficiency Virus–Associated Differences in the Tumor Immune Microenvironment of Lung, Breast, and Prostate Cancers
2025cited by 0position: contributordoi
Supplementary Tables S1-S3 from A Phase 1 First-in-Human Study of FS118, a Tetravalent Bispecific Antibody Targeting LAG-3 and PD-L1 in Patients with Advanced Cancer and PD-L1 Resistance
2025cited by 0position: contributordoi
Supplemental Figure 1 from Human Immunodeficiency Virus–Associated Differences in the Tumor Immune Microenvironment of Lung, Breast, and Prostate Cancers
2025cited by 0position: contributordoi
Supplementary Figures S1-S5 from A Phase 1 First-in-Human Study of FS118, a Tetravalent Bispecific Antibody Targeting LAG-3 and PD-L1 in Patients with Advanced Cancer and PD-L1 Resistance
2025cited by 0position: contributordoi
Supplementary Information S1 from A Phase 1 First-in-Human Study of FS118, a Tetravalent Bispecific Antibody Targeting LAG-3 and PD-L1 in Patients with Advanced Cancer and PD-L1 Resistance
2025cited by 0position: contributordoi
Data from A Phase 1 First-in-Human Study of FS118, a Tetravalent Bispecific Antibody Targeting LAG-3 and PD-L1 in Patients with Advanced Cancer and PD-L1 Resistance
2025cited by 0position: contributordoi
Supplemental Table 2 from Human Immunodeficiency Virus–Associated Differences in the Tumor Immune Microenvironment of Lung, Breast, and Prostate Cancers
2025cited by 0position: contributordoi
Lower frequencies of circulating suppressive regulatory T cells and higher frequencies of CD4<sup>+</sup> naïve T cells at baseline are associated with severe immune-related adverse events in immune checkpoint inhibitor-treated melanoma
Journal for ImmunoTherapy of Cancer 2024cited by 16position: lastdoi
Neoadjuvant–Adjuvant or Adjuvant-Only Pembrolizumab in Advanced Melanoma
New England Journal of Medicine 2023cited by 794position: middledoi
Ipilimumab with or without nivolumab in PD-1 or PD-L1 blockade refractory metastatic melanoma: a randomized phase 2 trial
Nature Medicine 2023cited by 156position: middledoi
A Phase 1 First-in-Human Study of FS118, a Tetravalent Bispecific Antibody Targeting LAG-3 and PD-L1 in Patients with Advanced Cancer and PD-L1 Resistance.
2023cited by 46position: contributordoi
Immune Resistance Mechanisms and the Road to Personalized Immunotherapy
American Society of Clinical Oncology Educational Book 2023cited by 30position: lastdoi
A single center case series of immune checkpoint inhibitor-induced type 1 diabetes mellitus, patterns of disease onset and long-term clinical outcome
Frontiers in Immunology 2023cited by 26position: lastdoi
The New NCI Precision Medicine Trials
Clinical Cancer Research 2023cited by 12position: middledoi
The New NCI Precision Medicine Trials.
2023cited by 11position: contributordoi
Supplementary Figures S1-S5 from A Phase 1 First-in-Human Study of FS118, a Tetravalent Bispecific Antibody Targeting LAG-3 and PD-L1 in Patients with Advanced Cancer and PD-L1 Resistance
2023cited by 0position: contributordoi
Supplementary Information S1 from A Phase 1 First-in-Human Study of FS118, a Tetravalent Bispecific Antibody Targeting LAG-3 and PD-L1 in Patients with Advanced Cancer and PD-L1 Resistance
2023cited by 0position: contributordoi
Supplementary Tables S1-S3 from A Phase 1 First-in-Human Study of FS118, a Tetravalent Bispecific Antibody Targeting LAG-3 and PD-L1 in Patients with Advanced Cancer and PD-L1 Resistance
2023cited by 0position: contributordoi
Supplementary Information S1 from A Phase 1 First-in-Human Study of FS118, a Tetravalent Bispecific Antibody Targeting LAG-3 and PD-L1 in Patients with Advanced Cancer and PD-L1 Resistance
2023cited by 0position: contributordoi
Supplementary Figures S1-S5 from A Phase 1 First-in-Human Study of FS118, a Tetravalent Bispecific Antibody Targeting LAG-3 and PD-L1 in Patients with Advanced Cancer and PD-L1 Resistance
2023cited by 0position: contributordoi
Data from A Phase 1 First-in-Human Study of FS118, a Tetravalent Bispecific Antibody Targeting LAG-3 and PD-L1 in Patients with Advanced Cancer and PD-L1 Resistance
2023cited by 0position: contributordoi
Supplementary Tables S1-S3 from A Phase 1 First-in-Human Study of FS118, a Tetravalent Bispecific Antibody Targeting LAG-3 and PD-L1 in Patients with Advanced Cancer and PD-L1 Resistance
2023cited by 0position: contributordoi
The role of biomarkers in personalized immunotherapy
Biomarker Research 2022cited by 108position: lastdoi
First-in-human study of an OX40 (ivuxolimab) and 4-1BB (utomilumab) agonistic antibody combination in patients with advanced solid tumors
Journal for ImmunoTherapy of Cancer 2022cited by 56position: middledoi
Neoadjuvant PD-1 blockade in patients with resectable desmoplastic melanoma (SWOG 1512).
Journal of Clinical Oncology 2022cited by 21position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Antoni Ribas · UCLA Medical Center18 papers (2014–2022) · 17 papers (2023–2025)Richard C.A. Sainson · AstraZeneca Medimmune12 papers (2023–2025)Louis Kayitalire · 12 papers (2023–2025)Daniel Gliddon · University of Reading12 papers (2023–2025)Sylwia Marshall · F-star Therapeutics12 papers (2023–2025)Patricia LoRusso · University of California San Francisco Medical Center12 papers (2023–2025)Roslin Russell · 12 papers (2023–2025)Christopher J. Shepherd · Cambridge University Hospitals NHS Foundation Trust12 papers (2023–2025)Kyriakos P. Papadopoulos · Urology San Antonio12 papers (2023–2025)Claire S. Reader · NuvOx Pharma (United States)12 papers (2023–2025)Cristian Gradinaru · 12 papers (2023–2025)Kin-Mei Leung · 12 papers (2023–2025)Timothy A. Yap · The University of Texas MD Anderson Cancer Center12 papers (2023–2025)Fiona Germaschewski · 12 papers (2023–2025)Urszula Grabowska · 12 papers (2023–2025)Michelle Morrow · CTI BioPharma (United Kingdom)12 papers (2023–2025)Claire J. Seal · NuvOx Pharma (United States)12 papers (2023–2025)Deborah J. Wong · University of California, Los Angeles12 papers (2023–2025)Neil Brewis · Mission Therapeutics (United Kingdom)12 papers (2023–2025)
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