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Mary J. Dunlop

Boston University · US
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Area of research
Molecular Biology · Genetics
Research interest
Research interests include Gene Regulatory Network Analysis, CRISPR and Genetic Engineering, Bacterial Genetics and Biotechnology, and Microbial Metabolic Engineering and Bioproduction.
h-index
31
citations
3,825
works
129
NIH funding
primary concept
email

Recent publications

Label-free nanoscopy of cell metabolism by ultrasensitive reweighted visible stimulated Raman scattering
Nature Methods 2025cited by 30position: middledoi
Cell-TRACTR: A transformer-based model for end-to-end segmentation and tracking of cells
PLoS Computational Biology 2025cited by 11position: lastdoi
Unique growth and morphology properties of Clade 5 Clostridioides difficile strains revealed by single-cell time-lapse microscopy
PLoS Pathogens 2025cited by 9position: middledoi
Deep model predictive control of gene expression in thousands of single cells
Nature Communications 2024cited by 32position: lastdoi
Light-inducible protein degradation in E. coli with the LOVdeg tag
eLife 2024cited by 17position: lastdoi
Red Light Responsive Cre Recombinase for Bacterial Optogenetics
ACS Synthetic Biology 2024cited by 10position: lastdoi
An optogenetic toolkit for light-inducible antibiotic resistance
Nature Communications 2023cited by 33position: lastdoi
Advances in linking single-cell bacterial stress response to population-level survival
Current Opinion in Biotechnology 2023cited by 28position: lastdoi
Longitudinal Single‐Cell Imaging of Engineered Strains with Stimulated Raman Scattering to Characterize Heterogeneity in Fatty Acid Production
Advanced Science 2023cited by 26position: lastdoi
Light-inducible protein degradation in E. coli with the LOVdeg tag
eLife 2023cited by 12position: lastdoi
Controlled Protein Activities with Viral Proteases, Antiviral Peptides, and Antiviral Drugs
ACS Chemical Biology 2023cited by 9position: middledoi
DeLTA 2.0: A deep learning pipeline for quantifying single-cell spatial and temporal dynamics
PLoS Computational Biology 2022cited by 111position: lastdoi
Dynamic gene expression and growth underlie cell-to-cell heterogeneity in <i>Escherichia coli</i> stress response
Proceedings of the National Academy of Sciences 2022cited by 91position: lastdoi
Deep Learning Concepts and Applications for Synthetic Biology
GEN Biotechnology 2022cited by 26position: lastdoi
Transcriptional Tuning of Mevalonate Pathway Enzymes to Identify the Impact on Limonene Production in <i>Escherichia coli</i>
ACS Omega 2022cited by 17position: lastdoi
Anticipating antibiotic resistance
Science 2022cited by 14position: lastdoi
Microsecond fingerprint stimulated Raman spectroscopic imaging by ultrafast tuning and spatial-spectral learning
Nature Communications 2021cited by 140position: middledoi
DeLTA: Automated cell segmentation, tracking, and lineage reconstruction using deep learning
PLoS Computational Biology 2020cited by 262position: lastdoi
Core Competencies for Undergraduates in Bioengineering and Biomedical Engineering: Findings, Consequences, and Recommendations
Annals of Biomedical Engineering 2020cited by 71position: middledoi
Light-Inducible Recombinases for Bacterial Optogenetics
ACS Synthetic Biology 2020cited by 62position: lastdoi
Programmable gene regulation for metabolic engineering using decoy transcription factor binding sites
Nucleic Acids Research 2020cited by 45position: lastdoi
Functional roles of microbial cell-to-cell heterogeneity and emerging technologies for analysis and control
Current Opinion in Microbiology 2020cited by 37position: lastdoi
Mapping the Role of AcrAB-TolC Efflux Pumps in the Evolution of Antibiotic Resistance Reveals Near-MIC Treatments Facilitate Resistance Acquisition
mSphere 2020cited by 28position: lastdoi
Distinct timescales of RNA regulators enable the construction of a genetic pulse generator
Biotechnology and Bioengineering 2019cited by 53position: middledoi
Cell-machine interfaces for characterizing gene regulatory network dynamics
Current Opinion in Systems Biology 2019cited by 50position: lastdoi
Forecasting cell fate during antibiotic exposure using stochastic gene expression
Communications Biology 2019cited by 31position: lastdoi
Heterogeneity in efflux pump expression predisposes antibiotic-resistant cells to mutation
Science 2018cited by 260position: lastdoi
Mathematical Modeling of RNA-Based Architectures for Closed Loop Control of Gene Expression
ACS Synthetic Biology 2018cited by 51position: middledoi
Controlling and exploiting cell-to-cell variation in metabolic engineering
Current Opinion in Biotechnology 2018cited by 32position: lastdoi
Antibiotic export by efflux pumps affects growth of neighboring bacteria
Scientific Reports 2018cited by 30position: lastdoi

Grants

Using optogenetics to characterize signal propagation and control within gene regulatory networks
NSF2533553$885,6422025–2028PIRePORTER
Optogenetic control for metabolic engineering using protein-level regulation
NSF2422796$519,0712025–2028PIRePORTER
Optogenetic selection for dynamic phenotypes in bacteria
NSF2324909$796,1582023–2027PIRePORTER
Transitions: Deep Learning Models for Microbial Image Analysis and Time-Series Predictions
NSF2143289$638,5782022–2025PIRePORTER
Single-cell feedback, optogenetics, and deep learning to control gene expression in bacteria
NSF2032357$820,2982020–2024PIRePORTER
Exploiting dynamics and cell-to-cell variation in metabolic engineering
NSF1804096$309,6092018–2022PIRePORTER
CAREER: Tunable Dynamics from Interlinked Feedback Loops in Synthetic and Natural Gene Circuits
NSF1740563$450,4792017–2020PIRePORTER
CAREER: Tunable Dynamics from Interlinked Feedback Loops in Synthetic and Natural Gene Circuits
NSF1347635$700,0002014–2017PIRePORTER

Frequent collaborators

Jean‐Baptiste Lugagne · Boston University9 papers (2019–2025)Nathan Tague · Boston University7 papers (2020–2024)Imane El Meouche · Tufts University4 papers (2018–2025)Haonan Lin · Boston University4 papers (2020–2025)Michael B. Sheets · Boston University4 papers (2020–2024)Ji‐Xin Cheng · Boston University3 papers (2021–2025)Wilson W. Wong · Boston University3 papers (2020–2023)Ariel M. Langevin · Boston University3 papers (2017–2020)Owen M. O’Connor · Boston University3 papers (2022–2025)Nadia M. V. Sampaio · Brazilian Center for Research in Energy and Materials2 papers (2020–2022)Razan N. Alnahhas · Boston University2 papers (2022–2023)Vincent Noireaux · University of Minnesota, Twin Cities2 papers (2018–2019)Caroline M. Blassick · Boston University2 papers (2022–2024)Xun Tang · Georgia Institute of Technology2 papers (2018–2019)Tiebin Wang · Northeast Forestry University2 papers (2018–2020)Alexandra Westbrook · Cornell University2 papers (2018–2019)Cristian Coriano-Ortiz · Boston University2 papers (2023–2024)Lei Tian · Shanghai University of Engineering Science2 papers (2021–2025)Ryan Marshall · University of Minnesota, Twin Cities2 papers (2018–2019)Elisa Franco · University of California, Los Angeles2 papers (2018–2019)
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