Area of research
Psychiatry and Mental health · Neurology
Research interest
Research interests include Dementia and Cognitive Impairment Research, Neurological Disease Mechanisms and Treatments, Acute Ischemic Stroke Management, and Alzheimer's disease research and treatments.
Clinical utility of plasma p‐tau217 in identifying abnormal brain amyloid burden in an Asian cohort with high prevalence of concomitant cerebrovascular disease
Plasma proteomics for cognitive decline and dementia—A Southeast Asian cohort study
A deep‐learning retinal aging biomarker for cognitive decline and incident dementia
Signature White Matter Hyperintensity Locations Associated With Vascular Risk Factors Derived From 15 653 Individuals
Blood-based biomarkers of cerebral small vessel disease
Amyloid pathology and vascular risk are associated with distinct patterns of cerebral white matter hyperintensities: A multicenter study in 3132 memory clinic patients
Risk prediction of cardiovascular disease in the Asia-Pacific region: the SCORE2 Asia-Pacific model
Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries
Genetic variants for head size share genes and pathways with cancer
Neuroimaging standards for research into small vessel disease—advances since 2013
Genomics of perivascular space burden unravels early mechanisms of cerebral small vessel disease
Lipidomics profiling reveals distinct patterns of plasma sphingolipid alterations in Alzheimer’s disease and vascular dementia
Brain atrophy and white matter hyperintensities are independently associated with plasma neurofilament light chain in an Asian cohort of cognitively impaired patients with concomitant cerebral small vessel disease
Sex Differences in Poststroke Cognitive Impairment: A Multicenter Study in 2343 Patients With Acute Ischemic Stroke
Deep learning based detection of enlarged perivascular spaces on brain MRI
White Matter Hyperintensity Volume and Poststroke Cognition: An Individual Patient Data Pooled Analysis of 9 Ischemic Stroke Cohort Studies
Assessment of Risk Factors and Clinical Importance of Enlarged Perivascular Spaces by Whole-Brain Investigation in the Multi-Ethnic Study of Atherosclerosis
Impact of Cerebral Microbleeds in Stroke Patients with Atrial Fibrillation
Chromosome 10q24.32 Variants Associate With Brain Arterial Diameters in Diverse Populations: A Genome‐Wide Association Study
The global burden of cerebral small vessel disease in low- and middle-income countries: A systematic review and meta-analysis
Strategic white matter hyperintensity locations for cognitive impairment: A multicenter lesion‐symptom mapping study in 3525 memory clinic patients
Determinants of Perivascular Spaces in the General Population
Low Plasma Ergothioneine Predicts Cognitive and Functional Decline in an Elderly Cohort Attending Memory Clinics
A Machine Learning Approach for Early Diagnosis of Cognitive Impairment Using Population-Based Data
Effects of Carotid Artery Stiffness on Cerebral Small‐Vessel Disease and Cognition
Cerebral Microbleeds, Cerebral Amyloid Angiopathy, and Their Relationships to Quantitative Markers of Neurodegeneration
A multi-regression framework to improve diagnostic ability of optical coherence tomography retinal biomarkers to discriminate mild cognitive impairment and Alzheimer’s disease
Network impact score is an independent predictor of post-stroke cognitive impairment: A multicenter cohort study in 2341 patients with acute ischemic stroke
Plasma amyloid-β40 in relation to subclinical atherosclerosis and cardiovascular disease: A population-based study
Strategic infarct locations for post-stroke cognitive impairment: a pooled analysis of individual patient data from 12 acute ischaemic stroke cohorts