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Dominic P. Williams

AstraZeneca (United Kingdom) · GB
Area of research
Pharmacology · Hepatology
Research interest
Research interests include Drug-Induced Hepatotoxicity and Protection, Pharmacogenetics and Drug Metabolism, Liver physiology and pathology, and Computational Drug Discovery Methods.
h-index
53
citations
8,968
works
175
NIH funding
primary concept
email

Recent publications

The hepatocyte export carrier inhibition assay improves the separation of hepatotoxic from non-hepatotoxic compounds
Chemico-Biological Interactions 2021cited by 24position: middledoi
Reproducing human and cross-species drug toxicities using a Liver-Chip
Science Translational Medicine 2019cited by 465position: middledoi
Managing the challenge of drug-induced liver injury: a roadmap for the development and deployment of preclinical predictive models
Nature Reviews Drug Discovery 2019cited by 244position: middledoi
Comparison of Hepatic 2D Sandwich Cultures and 3D Spheroids for Long-term Toxicity Applications: A Multicenter Study
Toxicological Sciences 2018cited by 308position: middledoi
Application of Microphysiological Systems to Enhance Safety Assessment in Drug Discovery
The Annual Review of Pharmacology and Toxicology 2017cited by 120position: middledoi
Concise Review: Workshop Review: Understanding and Assessing the Risks of Stem Cell-Based Therapies
Stem Cells Translational Medicine 2015cited by 136position: middledoi
RETRACTED: Molecular forms of HMGB1 and keratin-18 as mechanistic biomarkers for mode of cell death and prognosis during clinical acetaminophen hepatotoxicity
Journal of Hepatology 2012cited by 307position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Magnus Ingelman‐Sundberg · Karolinska Institutet3 papers (2017–2019) · 2 papers (2018–2021)Christopher E. Goldring · University of Liverpool2 papers (2018–2019) · 2 papers (2018–2019)Jan Snoeys · University of Minnesota, Twin Cities2 papers (2018–2019)Volker M. Lauschke · Karolinska University Hospital2 papers (2017–2018)Ursula Klingmüller · German Cancer Research Center1 papers (2019–2019)Amy Pointon · University of Leicester1 papers (2017–2017) · 1 papers (2017–2017) · 1 papers (2018–2018)Cristina Cadenas · TU Dortmund University1 papers (2021–2021)Karolina Edlund · TU Dortmund University1 papers (2021–2021) · 1 papers (2021–2021) · 1 papers (2017–2017)Amruta Damle‐Vartak · German Cancer Research Center1 papers (2021–2021) · 1 papers (2019–2019)Jörg Reinders · University of Regensburg1 papers (2021–2021) · 1 papers (2021–2021)Eric A.G. Blomme · AbbVie (United States)1 papers (2019–2019)Jörg Rahnenführer · TU Dortmund University1 papers (2021–2021)