Christian Rohde

Disrupting tRNA modifications to target mitochondrial vulnerabilities in drug-resistant leukemia cells

The landscape of RNA-chromatin interaction reveals small non-coding RNAs as essential mediators of leukemia maintenance

Clonally resolved single-cell multi-omics identifies routes of cellular differentiation in acute myeloid leukemia

The ribosomal protein S6 kinase alpha-1 (RPS6KA1) induces resistance to venetoclax/azacitidine in acute myeloid leukemia

Clonal hematopoiesis with <i>DNMT3A</i> and <i>PPM1D</i> mutations impairs regeneration in autologous stem cell transplant recipients

The landscape of small nucleolar RNA expression in multiple myeloma is determined by cytogenetic alterations

Data from A Dynamic rRNA Ribomethylome Drives Stemness in Acute Myeloid Leukemia

Venetoclax synergizes with gilteritinib in FLT3 wild-type high-risk acute myeloid leukemia by suppressing MCL-1

A Dynamic rRNA Ribomethylome Drives Stemness in Acute Myeloid Leukemia

Protein tyrosine kinase 2b inhibition reverts niche-associated resistance to tyrosine kinase inhibitors in AML

Clonally resolved single-cell multi-omics identifies routes of cellular differentiation in acute myeloid leukemia

PB1976: CRISPR-CAS9 KNOCKOUT SCREEN IDENTIFIES RNA MODIFICATION ENZYMES ESSENTIAL FOR CELL SURVIVAL IN MULTIPLE MYELOMA

Hotspot DNMT3A mutations in clonal hematopoiesis and acute myeloid leukemia sensitize cells to azacytidine via viral mimicry response

NOP10 predicts lung cancer prognosis and its associated small nucleolar RNAs drive proliferation and migration

Hepatic leukemia factor is a novel leukemic stem cell regulator in DNMT3A, NPM1, and FLT3-ITD triple-mutated AML

PS969 HYPOMETHYLATING DRUGS SPECIFICALLY TARGET DNMT3A MUTATION ASSOCIATED CLONAL HEMATOPOIESIS AND ACUTE MYELOID LEUKEMIA

AML1-ETO requires enhanced C/D box snoRNA/RNP formation to induce self-renewal and leukaemia

Aberrantly expressed stem cell associated protein PIWIL4 acts as a piRNA binding, epigenetically active and growth regulatory factor in human acute myeloid leukemia

Loss of the histone methyltransferase EZH2 induces resistance to multiple drugs in acute myeloid leukemia

Enantiomer-specific and paracrine leukemogenicity of mutant IDH metabolite 2-hydroxyglutarate

Increased DNA methylation of Dnmt3b targets impairs leukemogenesis

Alarmins MRP8 and MRP14 Induce Stress Tolerance in Phagocytes under Sterile Inflammatory Conditions

Prognostic Impact of Bcl-2 Depends on Tumor Histology and Expression of MALAT-1 lncRNA in Non–Small-Cell Lung Cancer

DNA Methyltransferase Inhibition Reverses Epigenetically Embedded Phenotypes in Lung Cancer Preferentially Affecting Polycomb Target Genes