Area of research
Molecular Biology · Cell Biology
Research interest
Research interests include Cellular transport and secretion, Lipid Membrane Structure and Behavior, Ion channel regulation and function, and Ion Transport and Channel Regulation.
Calcium-dependent ESCRT recruitment and lysosome exocytosis maintain epithelial integrity during Candida albicans invasion
Phagocytosis of Necrotic Debris at Sites of Injury and Inflammation
An Acquired and Endogenous Glycocalyx Forms a Bidirectional “Don’t Eat” and “Don’t Eat Me” Barrier to Phagocytosis
Transmembrane Pickets Connect Cyto- and Pericellular Skeletons Forming Barriers to Receptor Engagement
High-Throughput Screening Identifies Genes Required for <i>Candida albicans</i> Induction of Macrophage Pyroptosis
Membrane dynamics and organelle biogenesis—lipid pipelines and vesicular carriers
Integrins Form an Expanding Diffusional Barrier that Coordinates Phagocytosis
Multiphasic dynamics of phosphatidylinositol 4-phosphate during phagocytosis
Actin Cytoskeleton Reorganization by Syk Regulates Fcγ Receptor Responsiveness by Increasing Its Lateral Mobility and Clustering
The Haemophilus ducreyi LspA1 Protein Inhibits Phagocytosis By Using a New Mechanism Involving Activation of C-Terminal Src Kinase
Scavenger receptors in homeostasis and immunity
Multimolecular Signaling Complexes Enable Syk-Mediated Signaling of CD36 Internalization
Bem3, a Cdc42 GTPase-Activating Protein, traffics to an intracellular compartment and recruits the secretory Rab GTPase Sec4 to endomembranes
Lysosomal calcium homeostasis defects, not proton pump defects, cause endo-lysosomal dysfunction in PSEN-deficient cells
Phosphatidylserine dynamics in cellular membranes
Yersinia Entry into Host Cells Requires Rab5-Dependent Dephosphorylation of PI(4,5)P2 and Membrane Scission