Area of research
Genetics · Molecular Biology
Research interest
Research interests include Glioma Diagnosis and Treatment, Single-cell and spatial transcriptomics, Immune cells in cancer, and Neuroinflammation and Neurodegeneration Mechanisms.
Programs, origins and immunomodulatory functions of myeloid cells in glioma
Spatially resolved transcriptomics and graph-based deep learning improve accuracy of routine CNS tumor diagnostics
Extracellular Vesicles Carrying Tenascin-C are Clinical Biomarkers and Improve Tumor-Derived DNA Analysis in Glioblastoma Patients
AMP-activated protein kinase mediates adaptation of glioblastoma cells to conditions of the tumor microenvironment
Dual aVß8 Integrin and PD-1 Blockade Overcomes TGFβ-Mediated B-Cell Suppression to Enhance Anti-Tumor Immunity
Intraoperative classification of CNS lymphoma and glioblastoma by AI-based analysis of Stimulated Raman Histology (SRH)
Spatially resolved transcriptomics of benign and malignant peripheral nerve sheath tumors
Gasdermin E in glioblastoma –pyroptosis resistance and tumor-promoting functions
TMIC-81. Targeting TGFβ-mediated B cell suppression enhances anti-PD-1 efficacy in glioblastoma
A prognostic neural epigenetic signature in high-grade glioma
Characterizing and targeting glioblastoma neuron-tumor networks with retrograde tracing
Glioblastoma-instructed microglia transition to heterogeneous phenotypic states with phagocytic and dendritic cell-like features in patient tumors and patient-derived orthotopic xenografts
Glioblastoma cells increase expression of notch signaling and synaptic genes within infiltrated brain tissue
Cranioencephalic functional lymphoid units in glioblastoma
VC-resist glioblastoma cell state: vessel co-option as a key driver of chemoradiation resistance
Localization of protoporphyrin IX during glioma-resection surgery via paired stimulated Raman histology and fluorescence microscopy
Understanding glioblastoma at the single-cell level: Recent advances and future challenges
Comprehensive genetic profiling and molecularly guided treatment for patients with primary CNS tumors
Insights from a multicenter study on adult H3 K27M-mutated glioma: Surgical resection’s limited influence on overall survival, ATRX as molecular prognosticator
Effects of tumor treating fields (TTFields) on human mesenchymal stromal cells
An AMP‐activated protein kinase‐PGC‐1α axis mediates metabolic plasticity in glioblastoma
Mapping myeloid cell function: Spatial diversity in tumor and neuronal microenvironment
ARF4-mediated retrograde trafficking as a driver of chemoresistance in glioblastoma
Modulation of the Tumor Microenvironment By CCL19 in Primary CNS Lymphomas
Single-cell RNA sequencing and spatial transcriptomics reveal cancer-associated fibroblasts in glioblastoma with protumoral effects
EGFR promotes ALKBH5 nuclear retention to attenuate N6-methyladenosine and protect against ferroptosis in glioblastoma
Spatially resolved transcriptomic profiles reveal unique defining molecular features of infiltrative 5ALA-metabolizing cells associated with glioblastoma recurrence
Ribonucleotide reductase regulatory subunit M2 drives glioblastoma TMZ resistance through modulation of dNTP production
Sialic acid metabolism orchestrates transcellular connectivity and signaling in glioblastoma
Inhibition of ATR opposes glioblastoma invasion through disruption of cytoskeletal networks and integrin internalization via macropinocytosis