Area of research
Immunology · Neurology
Research interest
Research interests include Neuroinflammation and Neurodegeneration Mechanisms, Immune cells in cancer, Monoclonal and Polyclonal Antibodies Research, and Immune Cell Function and Interaction.
Functional studies with <scp>IgM</scp> and <scp>IgA</scp> immunoglobulins: binding to <scp>pIgR</scp>, <scp>FcαμR</scp>, <scp>FcμR,</scp> and <scp>CDC</scp> activities
Assessment of technical and clinical utility of a bead-based flow cytometry platform for multiparametric phenotyping of CNS-derived extracellular vesicles
Targeting sphingolipid metabolism with the sphingosine kinase inhibitor SKI-II overcomes hypoxia-induced chemotherapy resistance in glioblastoma cells: effects on cell death, self-renewal, and invasion
Multistability in Macrophage Activation Pathways and Metabolic Implications
MYC dosage compensation is mediated by miRNA-transcription factor interactions in aneuploid cancer
Metabolic and inflammatory reprogramming of macrophages by ONC201 translates in a pro‐inflammatory environment even in presence of glioblastoma cells
MiR-144 overexpression as a promising therapeutic strategy to overcome glioblastoma cell invasiveness and resistance to chemotherapy
Paclitaxel Treatment and Proprotein Convertase 1/3 (PC1/3) Knockdown in Macrophages is a Promising Antiglioma Strategy as Revealed by Proteomics and Cytotoxicity Studies
Comparative analysis of the effects of a sphingosine kinase inhibitor to temozolomide and radiation treatment on glioblastoma cell lines
Evaluation of Consistency in Spheroid Invasion Assays
A Novel Computer-Assisted Approach to evaluate Multicellular Tumor Spheroid Invasion Assay
Glioblastoma cells induce differential glutamatergic gene expressions in human tumor-associated microglia/macrophages and monocyte-derived macrophages
A sphingosine kinase inhibitor combined with temozolomide induces glioblastoma cell death through accumulation of dihydrosphingosine and dihydroceramide, endoplasmic reticulum stress and autophagy
High resistance to X-rays and therapeutic carbon ions in glioblastoma cells bearing dysfunctional ATM associates with intrinsic chromosomal instability
Glutathione peroxidase 1 activity dictates the sensitivity of glioblastoma cells to oxidative stress
In-silico Modelling of Tumour-Immune System Interactions for Glioblastomas
In-silico Modellierung der Immunantwort auf Hirntumorwachstum