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Sara Mostafavi

Canadian Institute for Advanced Research ·
Area of research
Molecular Biology · Genetics
Research interest
Research interests include Bioinformatics and Genomic Networks, Genetic Associations and Epidemiology, Gene expression and cancer classification, and Genomics and Chromatin Dynamics.
h-index
64
citations
35,264
works
226
NIH funding
primary concept
email

Recent publications

Contrasting genetic predisposition and diagnosis in psychiatric disorders: A multi-omic single-nucleus analysis of the human OFC
Science Advances 2025cited by 16position: middledoi
Cell subtype-specific effects of genetic variation in the Alzheimer’s disease brain
Nature Genetics 2024cited by 172position: middledoi
ExplaiNN: interpretable and transparent neural networks for genomics
Genome biology 2023cited by 47position: middledoi
Obtaining genetics insights from deep learning via explainable artificial intelligence
Nature Reviews Genetics 2022cited by 366position: lastdoi
ExplaiNN: interpretable and transparent neural networks for genomics
bioRxiv (Cold Spring Harbor Laboratory) 2022cited by 8position: middledoi
The neutrotime transcriptional signature defines a single continuum of neutrophils across biological compartments
Nature Communications 2021cited by 331position: middledoi
Gut CD4+ T cell phenotypes are a continuum molded by microbes, not by TH archetypes
Nature Immunology 2021cited by 180position: middledoi
Regional gray matter oligodendrocyte- and myelin-related measures are associated with differential susceptibility to stress-induced behavior in rats and humans
Translational Psychiatry 2021cited by 41position: middledoi
Large eQTL meta-analysis reveals differing patterns between cerebral cortical and cerebellar brain regions
Scientific Data 2020cited by 329position: middledoi
Meta-Analysis of the Alzheimer’s Disease Human Brain Transcriptome and Functional Dissection in Mouse Models
Cell Reports 2020cited by 326position: middledoi
Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank
Molecular Psychiatry 2020cited by 219position: middledoi
A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank
Nature Communications 2020cited by 124position: middledoi
Deconvolving the contributions of cell-type heterogeneity on cortical gene expression
PLoS Computational Biology 2020cited by 124position: lastdoi
Immune profile differences between chronic GVHD and late acute GVHD: results of the ABLE/PBMTC 1202 studies
Blood 2020cited by 67position: middledoi
The cis-Regulatory Atlas of the Mouse Immune System
Cell 2019cited by 436position: middledoi
Biological embedding of experience: A primer on epigenetics
Proceedings of the National Academy of Sciences 2019cited by 262position: middledoi
Accurate ethnicity prediction from placental DNA methylation data
Epigenetics & Chromatin 2019cited by 82position: middledoi
Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression
Biological Psychiatry 2019cited by 45position: middledoi
A novel classification system for research reporting in rare and progressive genetic conditions
Developmental Medicine & Child Neurology 2019cited by 8position: middledoi
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
Nature Genetics 2018cited by 3,285position: middledoi
A multi-omic atlas of the human frontal cortex for aging and Alzheimer’s disease research
Scientific Data 2018cited by 675position: middledoi
A molecular network of the aging human brain provides insights into the pathology and cognitive decline of Alzheimer’s disease
Nature Neuroscience 2018cited by 570position: firstdoi
Integrative transcriptome analyses of the aging brain implicate altered splicing in Alzheimer’s disease susceptibility
Nature Genetics 2018cited by 453position: middledoi
Epigenome-wide study uncovers large-scale changes in histone acetylation driven by tau pathology in aging and Alzheimer’s human brains
Nature Neuroscience 2018cited by 264position: middledoi
Multiplexed droplet single-cell RNA-sequencing using natural genetic variation
Nature Biotechnology 2017cited by 1,267position: middledoi
An xQTL map integrates the genetic architecture of the human brain's transcriptome and epigenome
Nature Neuroscience 2017cited by 534position: middledoi
Allele-specific expression reveals interactions between genetic variation and environment
Nature Methods 2017cited by 175position: middledoi
Integrative analyses of splicing in the aging brain: role in susceptibility to Alzheimer’s Disease
bioRxiv (Cold Spring Harbor Laboratory) 2017cited by 11position: middledoi
Parsing the Interferon Transcriptional Network and Its Disease Associations
Cell 2016cited by 345position: firstdoi
Effect of predicted protein-truncating genetic variants on the human transcriptome
Science 2015cited by 345position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Philip L. De Jager · Mayo Clinic in Florida8 papers (2016–2020)Chris Gaiteri · Rush University Medical Center4 papers (2017–2020)Jishu Xu · University of Michigan–Ann Arbor4 papers (2017–2018)Cristin McCabe · Broad Institute4 papers (2017–2018)Tracy L. Young‐Pearse · Rush University Medical Center4 papers (2017–2018)Xiaowei Zhu · Sun Yat-sen University4 papers (2013–2017)Hans‐Ulrich Klein · University Hospital Münster4 papers (2017–2018)Douglas F. Levinson · Stanford University4 papers (2013–2017)Bernard Ng · Rush University Medical Center4 papers (2017–2020)Alexis Battle · Johns Hopkins University4 papers (2013–2017)Lei Yu · Qiqihar Medical University3 papers (2017–2018)Gherman Novakovsky · Illumina (United States)3 papers (2022–2023)Wyeth W. Wasserman · University of British Columbia3 papers (2022–2023)Ellis Patrick · The University of Sydney3 papers (2017–2020)Towfique Raj · Mount Sinai Beth Israel3 papers (2016–2018)Oriol Fornés · University of British Columbia2 papers (2022–2023)James B. Potash · Johns Hopkins University2 papers (2013–2017)Eric E. Schadt · New York Proton Center2 papers (2017–2018)Sarah E. Sullivan · Touro University California2 papers (2018–2018)William Casazza · University of Massachusetts Chan Medical School2 papers (2020–2021)