Area of research
Cell Biology · Neurology
Research interest
Research interests include Microtubule and mitosis dynamics, Cellular transport and secretion, Vestibular and auditory disorders, and Olfactory and Sensory Function Studies.
The KIF3B/B/KAP3 tail domain specifically facilitates TRIM46 transport to the axon initial segment.
The hook-like adaptor and cargo-binding (HAC) domain in the kinesin-2 tail enables adaptor assembly and cargo recognition.
Mutations in the kinesin KIF12 promote MASH in humans and mice by disrupting lipogenic enzyme turnover.
The Hitchdock Domain in Kinesin-2 Tail Enables Adaptor Assembly and Cargo Binding
Kinesin-1 mediates proper ER folding of the Ca<sub>V</sub>1.2 channel and maintains mouse glucose homeostasis.
Kinesin-1 mediates proper ER folding of the Ca <sub>V</sub> 1.2 channel and maintains mouse glucose homeostasis
Nodal flow transfers polycystin to determine mouse left-right asymmetry.
The two-step cargo recognition mechanism of heterotrimeric kinesin.
KIF4 regulates neuronal morphology and seizure susceptibility via the PARP1 signaling pathway.
Leftward transfer of a chemosensory polycystin initiates left-dominant calcium signaling for lateralized embryonic development
A neuropathy‐associated kinesin KIF1A mutation hyper‐stabilizes the motor‐neck interaction during the ATPase cycle
A neuropathy-associated kinesin KIF1A mutation hyper-stabilizes the motor-neck interaction during the ATPase cycle.
KIF3B promotes a PI3K signaling gradient causing changes in a Shh protein gradient and suppressing polydactyly in mice.
Kinesin Kif3b mutation reduces NMDAR subunit NR2A trafficking and causes schizophrenia-like phenotypes in mice.
An activity-dependent local transport regulation via degradation and synthesis of KIF17 underlying cognitive flexibility.
Excess hydrogen sulfide and polysulfides production underlies a schizophrenia pathophysiology.
Enhanced carbonyl stress induces irreversible multimerization of CRMP2 in schizophrenia pathogenesis.
Autoinhibition of a Neuronal Kinesin UNC-104/KIF1A Regulates the Size and Density of Synapses
Abstracts from the 3rd International Genomic Medicine Conference (3rd IGMC 2015)