Area of research
Molecular Biology · Pharmaceutical Science
Research interest
Research interests include RNA Interference and Gene Delivery, Advanced Drug Delivery Systems, Retinal Development and Disorders, and Retinal Diseases and Treatments.
Melanin-Binding-Based Discovery of Topically Instilled Carbonic Anhydrase Inhibitors for Targeted Delivery and Prolonged Action in the Eye.
Repurposing Drug Metabolites into Dual β-Adrenergic Receptor–Carbonic Anhydrase Modulators as Potential Tools for Ocular Disorders
5-(Sulfamoyl)thien-2-yl 1,3-oxazole inhibitors of carbonic anhydrase II with hydrophilic periphery.
The prophylactic value of TNF-α inhibitors against retinal cell apoptosis and optic nerve axon loss after corneal surgery or trauma
Exploring the Impact of Morphology on the Properties of Biodegradable Nanoparticles and Their Diffusion in Complex Biological Medium.
Diffusion and Protein Corona Formation of Lipid-Based Nanoparticles in the Vitreous Humor: Profiling and Pharmacokinetic Considerations.
Pharmacokinetics of Pullulan–Dexamethasone Conjugates in Retinal Drug Delivery
Retinal neuroprotection by controlled release of a VCP inhibitor from self-assembled nanoparticles
Ultrasound and Microbubbles for the Treatment of Ocular Diseases: From Preclinical Research towards Clinical Application
Carboxylesterase Activities and Protein Expression in Rabbit and Pig Ocular Tissues.
Conformationally Constrained Peptides with High Affinity to the Vascular Endothelial Growth Factor.
Exploring the Impact of Morphology on the Properties of Biodegradable Nanoparticles and Their Diffusion in Complex Biological Medium
Intravitreal hydrogels for sustained release of therapeutic proteins
Intravitreal hydrogels for sustained release of therapeutic proteins.
Diffusion and Protein Corona Formation of Lipid-Based Nanoparticles in the Vitreous Humor: Profiling and Pharmacokinetic Considerations
In situ analysis of liposome hard and soft protein corona structure and composition in a single label-free workflow.
Light-Activated Liposomes Coated with Hyaluronic Acid as a Potential Drug Delivery System
Prodrug Approach for Posterior Eye Drug Delivery: Synthesis of Novel Ganciclovir Prodrugs and in Vitro Screening with Cassette Dosing.
Design and synthesis of lipid-mimetic cationic iridium complexes and their liposomal formulation for <i>in vitro</i> and <i>in vivo</i> application in luminescent bioimaging.
Inhibition of VCP preserves retinal structure and function in autosomal dominant retinal degeneration
Artificially cloaked viral nanovaccine for cancer immunotherapy
<i>In situ</i>analysis of liposome hard and soft protein corona structure and composition in a single label-free workflow
Establishment of an In Vitro-In Vivo Correlation for Melanin Binding and the Extension of the Ocular Half-Life of Small-Molecule Drugs.
Intravitreal Pharmacokinetics in Mice: SPECT/CT Imaging and Scaling to Rabbits and Humans.
Influence of Melanin Characteristics on Drug Binding Properties.
Distribution of Small Molecular Weight Drugs into the Porcine Lens: Studies on Imaging Mass Spectrometry, Partition Coefficients, and Implications in Ocular Pharmacokinetics.
Comment on "Topical Delivery of Avastin to the Posterior Segment of the Eye In Vivo Using Annexin A5-Associated Liposomes": Topical Liposomal Bevacizumab Results in Negligible Retinal Concentrations.
ISOPT <i>Clinical</i> Hot Topic Panel Discussion on Ocular Drug Delivery
Loss of NRF-2 and PGC-1α genes leads to retinal pigment epithelium damage resembling dry age-related macular degeneration
The effect of light sensitizer localization on the stability of indocyanine green liposomes