Area of research
Molecular Biology · Cell Biology
Research interest
Research interests include Sphingolipid Metabolism and Signaling, Endoplasmic Reticulum Stress and Disease, Nitric Oxide and Endothelin Effects, and Lipid Membrane Structure and Behavior.
Ablation of <i>Prdm16</i> and beige fat identity causes vascular remodeling and elevated blood pressure
Suppression of endothelial ceramide de novo biosynthesis by Nogo-B contributes to cardiometabolic diseases
Rewiring Endothelial Sphingolipid Metabolism to Favor S1P Over Ceramide Protects From Coronary Atherosclerosis
High fat diet ameliorates mitochondrial cardiomyopathy in CHCHD10 mutant mice
Sphingosine‐1‐phosphate controls endothelial sphingolipid homeostasis via ORMDL
Endothelial Sphingolipid De Novo Synthesis Controls Blood Pressure by Regulating Signal Transduction and NO via Ceramide
Molecular determinants of nephron vascular specialization in the kidney
Structural basis of Ca2+-dependent activation and lipid transport by a TMEM16 scramblase
Targeting skeletal endothelium to ameliorate bone loss
ADAM10 controls the differentiation of the coronary arterial endothelium
S1PR1 (Sphingosine-1-Phosphate Receptor 1) Signaling Regulates Blood Flow and Pressure
An engineered S1P chaperone attenuates hypertension and ischemic injury
Impaired endothelial barrier function in apolipoprotein M‐deficient mice is dependent on sphingosine‐1‐phosphate receptor 1
Nogo-B regulates endothelial sphingolipid homeostasis to control vascular function and blood pressure
eNOS derived nitric oxide regulates endothelial barrier function via VE cadherin and Rho GTPases
Normal glucose uptake in the brain and heart requires an endothelial cell-specific HIF-1α–dependent function