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Mingdong Huang

Aarhus University · DK
Area of research
Cancer Research · Biomedical Engineering
Research interest
Research interests include Chemistry, Amiloride, Plasminogen activator, Membrane, Urokinase receptor, and In silico.
h-index
citations
145
works
8
NIH funding
primary concept
email

Recent publications

Modifying Antimicrobial Peptides with Albumin-Binding Molecules Enhances Membrane-Disrupting Efficacy by Modulating the Secondary Structure
Journal of Medicinal Chemistry 2025cited by 4position: middledoi
Endoplasmic Reticulum Protein 72 Regulates Integrin Mac-1 Activity to Influence Neutrophil Recruitment
Arteriosclerosis Thrombosis and Vascular Biology 2024cited by 17position: middledoi
Interface-driven structural evolution on diltiazem as novel uPAR inhibitors: from in silico design to in vitro evaluation
Molecular Diversity 2024cited by 5position: middledoi
Exploring the mechanism of photosensitizer conjugation on membrane perturbation of antimicrobial peptide: A multiscale molecular simulation study
International Journal of Biological Macromolecules 2023cited by 14position: middledoi
<i>In silico</i> screening of natural products as uPAR inhibitors via multiple structure-based docking and molecular dynamics simulations
Journal of Biomolecular Structure and Dynamics 2023cited by 3position: middledoi
Disruption of Water Networks is the Cause of Human/Mouse Species Selectivity in Urokinase Plasminogen Activator (uPA) Inhibitors Derived from Hexamethylene Amiloride (HMA)
Journal of Medicinal Chemistry 2021cited by 7position: middledoi
6-Substituted amiloride derivatives as inhibitors of the urokinase-type plasminogen activator for use in metastatic disease
Bioorganic & Medicinal Chemistry Letters 2019cited by 26position: middledoi
6-Substituted Hexamethylene Amiloride (HMA) Derivatives as Potent and Selective Inhibitors of the Human Urokinase Plasminogen Activator for Use in Cancer
Journal of Medicinal Chemistry 2018cited by 69position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Longguang Jiang · Aarhus University5 papers (2018–2025)Jinyu Li · Université Claude Bernard Lyon 14 papers (2023–2025)Yichang Liu · Heilongjiang University of Chinese Medicine4 papers (2023–2025)Peng Xu · Shandong University4 papers (2023–2025) · 3 papers (2023–2025)Benjamin J. Buckley · University of Wollongong3 papers (2018–2021)Michael J. Kelso · The University of Texas Southwestern Medical Center3 papers (2018–2021)Marie Ranson · University of Manchester3 papers (2018–2021) · 3 papers (2023–2025)Karen Fildes · University of Wollongong2 papers (2018–2019)Elahe Minaei · University of Wollongong2 papers (2018–2019)Song Xie · Shandong University2 papers (2023–2023) · 2 papers (2018–2019)Ashraf Aboelela · University of Wollongong2 papers (2018–2019)Chen‐Yi Cheung · University of Otago2 papers (2018–2019)Meiru Song · Anhui Medical University2 papers (2023–2025)Gregory M. Cook · Guangzhou Institutes of Biomedicine and Health2 papers (2018–2019)Yang Zhou · Fudan University2 papers (2023–2024)Daniel A. Bachovchin · Memorial Sloan Kettering Cancer Center2 papers (2018–2019)Umar Ali · University of Wollongong1 papers (2018–2018)