Area of research
Immunology · Oncology
Research interest
Research interests include interferon and immune responses, Cytokine Signaling Pathways and Interactions, Cancer Mechanisms and Therapy, and Immune cells in cancer.
Reprogramming of nucleotide metabolism by interferon confers dependence on the replication stress response pathway in pancreatic cancer cells
NAD <sup>+</sup> depletion by type I interferon signaling sensitizes pancreatic cancer cells to NAMPT inhibition
Histone deacetylase inhibition is synthetically lethal with arginine deprivation in pancreatic cancers with low argininosuccinate synthetase 1 expression
Metabolic Modifier Screen Reveals Secondary Targets of Protein Kinase Inhibitors within Nucleotide Metabolism
ATR inhibition facilitates targeting of leukemia dependence on convergent nucleotide biosynthetic pathways
[<sup>18</sup>F]CFA as a clinically translatable probe for PET imaging of deoxycytidine kinase activity
LKB1 Inactivation Dictates Therapeutic Response of Non-Small Cell Lung Cancer to the Metabolism Drug Phenformin