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Jennie H. M. Yang

Guy's Hospital ·
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Area of research
Genetics · Immunology
Research interest
Research interests include Diabetes and associated disorders, Diabetes Management and Research, Immune Cell Function and Interaction, and T-cell and B-cell Immunology.
h-index
21
citations
5,565
works
40
NIH funding
primary concept
email

Recent publications

The efficacy and safety of ustekinumab in adolescents newly diagnosed with type 1 diabetes: the USTEK1D RCT
Efficacy and Mechanism Evaluation 2025cited by 1position: middledoi
Ustekinumab for type 1 diabetes in adolescents: a multicenter, double-blind, randomized phase 2 trial
Nature Medicine 2024cited by 39position: middledoi
Low-dose IL-2 reduces IL-21+ T cell frequency and induces anti-inflammatory gene expression in type 1 diabetes
Nature Communications 2022cited by 35position: middledoi
Phase II multicentre, double-blind, randomised trial of ustekinumab in adolescents with new-onset type 1 diabetes (USTEK1D): trial protocol
BMJ Open 2021cited by 12position: middledoi
Chronic Immune Activation in Systemic Lupus Erythematosus and the Autoimmune PTPN22 Trp620 Risk Allele Drive the Expansion of FOXP3+ Regulatory T Cells and PD-1 Expression
Frontiers in Immunology 2019cited by 44position: middledoi
Metabolic and immune effects of immunotherapy with proinsulin peptide in human new-onset type 1 diabetes
Science Translational Medicine 2017cited by 213position: middledoi
IL-2 therapy restores regulatory T-cell dysfunction induced by calcineurin inhibitors
Proceedings of the National Academy of Sciences 2017cited by 119position: middledoi
Regulatory T Cell Responses in Participants with Type 1 Diabetes after a Single Dose of Interleukin-2: A Non-Randomised, Open Label, Adaptive Dose-Finding Trial
PLoS Medicine 2016cited by 136position: middledoi
Natural Variation in Interleukin-2 Sensitivity Influences Regulatory T-Cell Frequency and Function in Individuals With Long-standing Type 1 Diabetes
Diabetes 2015cited by 58position: firstdoi
Clinical-Grade Multipotent Adult Progenitor Cells Durably Control Pathogenic T Cell Responses in Human Models of Transplantation and Autoimmunity
The Journal of Immunology 2013cited by 71position: middledoi
Type 1 Diabetes-Associated <i>IL2RA</i> Variation Lowers IL-2 Signaling and Contributes to Diminished CD4+CD25+ Regulatory T Cell Function
The Journal of Immunology 2012cited by 205position: middledoi
Statistical colocalization of monocyte gene expression and genetic risk variants for type 1 diabetes
Human Molecular Genetics 2012cited by 116position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Timothy Tree · King's College London8 papers (2012–2025)John A. Todd · Centre for Human Genetics5 papers (2012–2022)Linda S. Wicker · Centre for Human Genetics4 papers (2012–2022)Ricardo C. Ferreira · Centre for Human Genetics3 papers (2015–2022)Marcin Ł. Pękalski · Centre for Human Genetics3 papers (2012–2022)John W Gregory · New York University2 papers (2021–2025)Greg Fegan · London School of Hygiene & Tropical Medicine2 papers (2021–2025)Dominik Trzupek · Oxford BioMedica (United Kingdom)2 papers (2019–2022)Ashish Marwaha · Hospital for Sick Children2 papers (2021–2025)Hayley Hutchings · Swansea University2 papers (2021–2025)James L. Reading · Cancer Research UK2 papers (2013–2015)Deborah J. Smyth · Centre for Human Genetics2 papers (2012–2015)Gail Holland · Swansea University2 papers (2021–2025) · 2 papers (2012–2019)Chris Wallace · University of Cambridge2 papers (2012–2015)Kymberley Carter · Swansea University2 papers (2021–2025)Danijela Tatović · Centre for Human Genetics2 papers (2021–2025)Jane Bowen‐Morris · Cardiff University2 papers (2021–2025)Colin Dayan · KU Leuven2 papers (2021–2025)Stephen D. Luzio · University of Birmingham2 papers (2021–2025)
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