Area of research
Molecular Biology · Rheumatology
Research interest
Research interests include Bone Metabolism and Diseases, TGF-β signaling in diseases, Osteoarthritis Treatment and Mechanisms, and Spine and Intervertebral Disc Pathology.
Parathyroid hormone treatment partially reverses endplate remodeling and attenuates low back pain in animal models of spine degeneration
Subchondral bone in knee osteoarthritis: bystander or treatment target?
Statin use and longitudinal changes in quantitative MRI-based biomarkers of thigh muscle quality: data from Osteoarthritis Initiative
Divalent metal cations stimulate skeleton interoception for new bone formation in mouse injury models
Role of Thigh Muscle Changes in Knee Osteoarthritis Outcomes: Osteoarthritis Initiative Data
Senescent preosteoclast secretome promotes metabolic syndrome associated osteoarthritis through cyclooxygenase 2
Dendritic cell immunoreceptor drives atopic dermatitis by modulating oxidized CaMKII-involved mast cell activation
Mechanical stress determines the configuration of TGFβ activation in articular cartilage
Cellular senescence in musculoskeletal homeostasis, diseases, and regeneration
PGE2/EP4 skeleton interoception activity reduces vertebral endplate porosity and spinal pain with low-dose celecoxib
Parathyroid hormone attenuates osteoarthritis pain by remodeling subchondral bone in mice
Angiogenesis stimulated by elevated PDGF-BB in subchondral bone contributes to osteoarthritis development
Sensory nerves regulate mesenchymal stromal cell lineage commitment by tuning sympathetic tones
Aberrant subchondral osteoblastic metabolism modifies NaV1.8 for osteoarthritis
Prostaglandin E2 mediates sensory nerve regulation of bone homeostasis
Macrophage-lineage TRAP+ cells recruit periosteum-derived cells for periosteal osteogenesis and regeneration
Sensory innervation in porous endplates by Netrin-1 from osteoclasts mediates PGE2-induced spinal hypersensitivity in mice
Inhibition of cyclooxygenase-2 activity in subchondral bone modifies a subtype of osteoarthritis
Subchondral bone osteoclasts induce sensory innervation and osteoarthritis pain
Inhibition of overactive TGF-β attenuates progression of heterotopic ossification in mice
Ciliary parathyroid hormone signaling activates transforming growth factor-β to maintain intervertebral disc homeostasis during aging
MiR-497∼195 cluster regulates angiogenesis during coupling with osteogenesis by maintaining endothelial Notch and HIF-1α activity
Mannose receptor modulates macrophage polarization and allergic inflammation through miR-511-3p
Mechanosignaling activation of TGFβ maintains intervertebral disc homeostasis
Halofuginone attenuates osteoarthritis by inhibition of TGF-β activity and H-type vessel formation in subchondral bone
PDGF-BB secreted by preosteoclasts induces angiogenesis during coupling with osteogenesis
Inhibition of TGF-β signaling in mesenchymal stem cells of subchondral bone attenuates osteoarthritis
Matrix IGF-1 maintains bone mass by activation of mTOR in mesenchymal stem cells
Parathyroid hormone induces differentiation of mesenchymal stromal/stem cells by enhancing bone morphogenetic protein signaling
Injury‐Activated Transforming Growth Factor β Controls Mobilization of Mesenchymal Stem Cells for Tissue Remodeling