Area of research
Immunology and Allergy · Cell Biology
Research interest
Research interests include Cell Adhesion Molecules Research, Cellular Mechanics and Interactions, Connective tissue disorders research, and Axon Guidance and Neuronal Signaling.
Furin-like cleavage at the C1-C2 linker region of the ⍺3 chain is not required for collagen VI assembly
Tenascin-C orchestrates radiotherapy-induced head and neck tumor regression.
Persistent epigenetic memory of SARS-CoV-2 mRNA vaccination in monocyte-derived macrophages.
Prodomain processing controls BMP-10 bioactivity and targeting to fibrillin-1 in latent conformation.
Fibre type differences in the organisation of mononuclear cells and myonuclei at the tips of human myofibres.
SVEP1 enables efficient binding of Angiopoietin-2 to the TIE1 receptor, allowing receptor phosphorylation and downstream signaling
Vitamin D-inducible antimicrobial peptide LL-37 binds SARS-CoV-2 Spike and accessory proteins ORF7a and ORF8.
Collagen XII deficiency promotes ligament-specific heterotopic ossification via fibrochondrocyte differentiation.
Ehlers-Danlos Syndromes and Related Disorders: Diagnostic Challenges and the Need for an Interdisciplinary Patient Care in Germany.
Targeting IL6-Edn1-FoxO1 axis enables lung growth in mechanically ventilated newborn mice.
High rate of RNAemia and impaired immunity in patients with immunodeficiency in the vaccination era.
Identification of FasL as a crucial host factor driving COVID-19 pathology and lethality.
The unique ORF8 protein from SARS-CoV-2 binds to human dendritic cells and induces a hyper-inflammatory cytokine storm.
Spatial proteomics of skeletal muscle using thin cryosections reveals metabolic adaptation at the muscle-tendon transition zone.
Discovery of dual-active ethionamide boosters inhibiting the Mycobacterium tuberculosis ESX-1 secretion system.
Dual topologies of myotomal collagen XV and Tenascin C act in concert to guide and shape developing motor axons.
A novel homozygous nonsense variant in COL12A1 causes myopathic Ehlers-Danlos syndrome: A case report and literature review.
Osteoclast-specific Plastin 3 knockout in mice fail to develop osteoporosis despite dramatic increased osteoclast resorption activity.
Identifying the molecular basis of Laminin N-terminal domain Ca<sup>2+</sup> binding using a hybrid approach.
Fibre type differences in the organisation of mononuclear cells and myonuclei at the tips of human myofibres
Discovery of highly neutralizing human antibodies targeting Pseudomonas aeruginosa
Enhanced SARS-CoV-2 humoral immunity following breakthrough infection builds upon the preexisting memory B cell pool.
Distinct myofibre domains of the human myotendinous junction revealed by single-nucleus RNA sequencing.
Discovery of highly neutralizing human antibodies targeting Pseudomonas aeruginosa.
Somatic hypermutation introduces bystander mutations that prepare SARS-CoV-2 antibodies for emerging variants.
Svep1 is a binding ligand of Tie1 and affects specific aspects of facial lymphatic development in a Vegfc-independent manner.
Fibroblast-derived matrix models desmoplastic properties and forms a prognostic signature in cancer progression.
Larger interface area at the human myotendinous junction in type 1 compared with type 2 muscle fibers.
Single-cell analysis of memory B cells from top neutralizers reveals multiple sites of vulnerability within HCMV Trimer and Pentamer.
The dynamic nature of netrin-1 and the structural basis for glycosaminoglycan fragment-induced filament formation.