Area of research
Pharmacology · Biotechnology
Research interest
Research interests include Microbial Natural Products and Biosynthesis, Marine Sponges and Natural Products, Fungal Biology and Applications, and Synthesis and Biological Activity.
Discovery of an Indole-Quinazoline Alkaloid as an Anti-kidney Fibrotic Agent from the Marine-Derived <i>Aspergillus clavatonanicus</i> SCSIO 41444.
Chemical Diversity and Antitumor Metabolites from Soft Coral-Derived Fungus <i>Aspergillus sclerotiorum</i> SCSIO 41031 via OSMAC Strategy.
Two New Pentadepsipeptides from the Mangrove Fungus <i>Aspergillus</i> sp. SCSIO 41443.
Advances in Natural Products from Mangrove-Associated Fungi Along the Indian Ocean Coast.
Diverse and Bioactive Lactones from the Sri Lankan Mangrove-Derived Fungus <i>Talaromyces</i> sp. SCSIO41445.
Two new prenylated tryptophan analogues isolated from the coral-derived fungus
<i>Tritirachium</i>
sp. SCSIO 41037
Discovery of a Hepatoprotective Trinor-Sesterterpenoid from the Marine Fungus Talaromyces sp. Against Hepatic Ischemia-Reperfusion Injury
Glucose Metabolic Reprogramming in Colorectal Cancer: From Mechanisms to Targeted Therapy Approaches
Two new Aspera chaetominines A and B, and a new derivative of terrein, isolated from marine sponge associated fungus <i>Aspergillus versicolour</i> SCSIO XWS04 F52.
Isoechinulin-Type Diketopiperazines with Anti-monocyte Adhesion Activities from a Sponge-Associated <i>Aspergillus</i> sp
Pyripyropene U, a new alkaloid from the sponge-derived fungus <i>Aspergillus</i> sp. SCSIO41420.
Evaluation of pharmacokinetics and metabolism of three marine-derived piericidins for guiding drug lead selection
Discovery of a Hepatoprotective Trinor-Sesterterpenoid from the Marine Fungus <i>Talaromyces</i> sp. Against Hepatic Ischemia-Reperfusion Injury.
Antiosteoclastogenic Indole Alkaloids from the Mangrove Endophytic Fungus <i>Penicillium brefeldianum</i> GXIMD 02511.
Sorbicillalanines A and B, Two [6,5,6] Hybrid-Sorbicillinoid Alkaloids from Deep-Sea-Derived <i>Penicillium</i> sp. Co-Cultured with Sponge-Derived <i>Setosphaeria</i> sp.
From monomers to pentamers, diverse antimicrobial benzofuran polyketides from marine-derived
<i>Striaticonidium cinctum</i>
Three New Phenyl Ether Derivatives From the Deep‐Sea‐Derived Fungus <i>Aspergillus</i> sp. SCSIO 41230
Prenylated xanthones from the coral-derived fungus <i>Aspergillus stellatus</i> SCSIO41406 and their antibacterial activities.
Novel Cyclic Tetrapeptides as Neuraminidase Inhibitors from a Sponge-Associated <i>Penicillium</i> sp. SCSIO41035.
New Polyketide and Butenolide Derivatives from the Mangrove Fungus <i>Aspergillus spelaeus</i> SCSIO 41433.
New Polyketides from a Marine Sponge-Derived Fungus, <i>Neopestalotiopsis</i> sp., with Anti-Renal Fibrosis Activity.
Targeting YY1-DR5 Axis by Pyripyropene O as a Novel Therapeutic Strategy Against Prostate Cancer: Molecular Mechanisms and In Vivo Zebrafish Validation.
The combination of PD-1 inhibitor with chemotherapy ± salvage chemoradiotherapy for local primary-recurrence esophageal squamous cell carcinoma after definitive chemoradiotherapy: A prospective, multicenter, single-arm clinical study (ESO-Nanjing12).
Cytotoxic Cytochalasans from Sponge-Derived <i>Aspergillus</i> sp. SCSIO 41044.
Isoechinulin-Type Diketopiperazines with Anti-monocyte Adhesion Activities from a Sponge-Associated <i>Aspergillus</i> sp.
Striasteroids A-C, Three Hybrid Steroids with Neuraminidase Inhibitory Activities from a Marine-Derived <i>Striaticonidium cinctum</i>.
Discovery of a novel anti-osteoporotic agent from marine fungus-derived structurally diverse sirenins
Identifying Marine-Derived Tanzawaic Acid Derivatives as Novel Inhibitors against Osteoclastogenesis and Osteoporosis via Downregulation of NF-κB and NFATc1 Activation.
A novel marine-derived anti-acute kidney injury agent targeting peroxiredoxin 1 and its nanodelivery strategy based on ADME optimization
Peniditerpenoids A and B: Oxidized Indole Diterpenoids with Osteoclast Differentiation Inhibitory Activity from a Mangrove-Sediment-Derived <i>Penicillium</i> sp.