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G. Aaron Hobbs

Medical University of South Carolina · US
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Area of research
Molecular Biology · Oncology
Research interest
Research interests include Protein Kinase Regulation and GTPase Signaling, Pancreatic and Hepatic Oncology Research, CRISPR and Genetic Engineering, and Protein Degradation and Inhibitors.
h-index
21
citations
6,088
works
109
NIH funding
primary concept
KRAS
email

Recent publications

STAT3 in tumor fibroblasts promotes an immunosuppressive microenvironment in pancreatic cancer
Life Science Alliance 2022cited by 48position: middledoi
Functional and biological heterogeneity of KRAS <sup>Q61</sup> mutations
Science Signaling 2022cited by 43position: middledoi
Identification of the nucleotide-free state as a therapeutic vulnerability for inhibition of selected oncogenic RAS mutants
Cell Reports 2022cited by 22position: middledoi
Altered RNA Splicing by Mutant p53 Activates Oncogenic RAS Signaling in Pancreatic Cancer
Cancer Cell 2020cited by 156position: middledoi
Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer
Nature Medicine 2019cited by 707position: middledoi
Evaluation of the selectivity and sensitivity of isoform- and mutation-specific RAS antibodies
Science Signaling 2017cited by 66position: middledoi
RAS isoforms and mutations in cancer at a glance
Journal of Cell Science 2016cited by 983position: firstdoi
Copper is required for oncogenic BRAF signalling and tumorigenesis
Nature 2014cited by 592position: middledoi
Glutathiolated Ras: Characterization and implications for Ras activation
Free Radical Biology and Medicine 2012cited by 36position: firstdoi

Grants

No grants ingested yet.

Frequent collaborators

Sharon L. Campbell · University of North Carolina at Chapel Hill3 papers (2012–2022)Channing J. Der · University of North Carolina at Chapel Hill3 papers (2016–2022)Adrienne D. Cox · University of North Carolina at Chapel Hill2 papers (2017–2022)Andrew M. Waters · University of North Carolina at Chapel Hill2 papers (2017–2022)Akiko Koide · NYU Langone Health1 papers (2022–2022)Matthew S. Crowe · Novartis (Switzerland)1 papers (2014–2014)Peter J. Houghton · The University of Texas Health Science Center at San Antonio1 papers (2017–2017)Mariaelena Pierobon · George Mason University1 papers (2022–2022)A. Chaikuad · Goethe University Frankfurt1 papers (2014–2014)Kent L. Rossman · University of North Carolina at Chapel Hill1 papers (2016–2016)Lin Lin · University of Michigan–Ann Arbor1 papers (2022–2022) · 1 papers (2014–2014)Leiah M. Carey · North Carolina State University1 papers (2022–2022)J. Nathaniel Diehl · University of North Carolina at Chapel Hill1 papers (2022–2022)Imran Khan · University of Illinois Chicago1 papers (2022–2022)Frank McCormick · UCSF Helen Diller Family Comprehensive Cancer Center1 papers (2017–2017)Maria C. Cuitiño · The Ohio State University1 papers (2022–2022)John P. O’Bryan · University of Illinois Chicago1 papers (2022–2022)David G. Huntsman · Huntsman Marine Science Centre1 papers (2017–2017)Costas A. Lyssiotis · University of Washington Applied Physics Laboratory1 papers (2022–2022)
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