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David T. Jones

Institute of Structural and Molecular Biology · GB
Area of research
Molecular Biology · Materials Chemistry · protein folding alphafold
Research interest
Research interests include Protein Structure and Dynamics, Machine Learning in Bioinformatics, RNA and protein synthesis mechanisms, and Enzyme Structure and Function.
h-index
94
citations
54,063
works
368
NIH funding
primary concept
Biology
email

Recent publications

AlphaFold Protein Structure Database 2025: a redesigned interface and updated structural coverage.
2026cited by 5position: contributordoi
On the state of protein function prediction: a report on the fourth CAFA challenge
2026cited by 0position: contributordoi
Metagenomic-scale analysis of the predicted protein structure universe
2026cited by 0position: contributordoi
Metagenomic-scale analysis of the predicted protein structure universe
2025cited by 7position: contributordoi
Foldclass and Merizo-search: scalable structural similarity search for single- and multi-domain proteins using geometric learning.
2025cited by 2position: contributordoi
Exploring structural diversity across the protein universe with The Encyclopedia of Domains.
2024cited by 85position: contributordoi
Exploring structural diversity across the protein universe with The Encyclopedia of Domains
2024cited by 11position: contributordoi
Foldclass and Merizo-search: embedding-based deep learning tools for protein domain segmentation, fold recognition and comparison
2024cited by 8position: contributordoi
Merizo: a rapid and accurate protein domain segmentation method using invariant point attention.
2023cited by 39position: contributordoi
Machine learning methods for predicting protein structure from single sequences
Current Opinion in Structural Biology 2023cited by 23position: contributordoi
Merizo: a rapid and accurate domain segmentation method using invariant point attention
2023cited by 1position: contributordoi
A guide to machine learning for biologists.
2022cited by 1,138position: contributordoi
The impact of AlphaFold2 one year on.
2022cited by 112position: contributordoi
Design in the DARK: Learning Deep Generative Models for De Novo Protein Design
2022cited by 24position: contributordoi
Ultrafast end-to-end protein structure prediction enables high-throughput exploration of uncharacterized proteins.
2022cited by 23position: contributordoi
A guide to machine learning for biologists
Nature Reviews Molecular Cell Biology 2021cited by 2,025position: lastdoi
Critical assessment of protein intrinsic disorder prediction
Nature Methods 2021cited by 359position: middledoi
Increasing the accuracy of single sequence prediction methods using a deep semi-supervised learning framework.
2021cited by 48position: contributordoi
Using AlphaFold for Rapid and Accurate Fixed Backbone Protein Design
2021cited by 32position: contributordoi
Differentiable molecular simulation can learn all the parameters in a coarse-grained force field for proteins
2021cited by 2position: contributordoi
Improved protein structure prediction using potentials from deep learning
Nature 2020cited by 3,490position: middledoi
Protein function prediction is improved by creating synthetic feature samples with generative adversarial networks
Nature Machine Intelligence 2020cited by 72position: contributordoi
Ultrafast end-to-end protein structure prediction enables high-throughput exploration of uncharacterised proteins
2020cited by 7position: contributordoi
A Deep Semi-Supervised Framework for Accurate Modelling of Orphan Sequences
2020cited by 1position: contributordoi
The CAFA challenge reports improved protein function prediction and new functional annotations for hundreds of genes through experimental screens
Genome biology 2019cited by 478position: middledoi
Setting the standards for machine learning in biology.
2019cited by 69position: contributordoi
Framework engineering to produce dominant T cell receptors with enhanced antigen-specific function.
2019cited by 48position: contributordoi
Prediction of inter-residue contacts with DeepMetaPSICOV in CASP13
2019cited by 7position: contributordoi
Working toward precision medicine: Predicting phenotypes from exomes in the Critical Assessment of Genome Interpretation (CAGI) challenges
Human Mutation 2017cited by 50position: middledoi
An expanded evaluation of protein function prediction methods shows an improvement in accuracy
Genome biology 2016cited by 450position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

· 23 papers (2019–2026)Shaun M. Kandathil · University College London14 papers (2019–2026)Andy M. Lau · University College London8 papers (2020–2026)Joe G. Greener · MRC Laboratory of Molecular Biology5 papers (2019–2022)Nicola Bordin · Institute of Structural and Molecular Biology5 papers (2024–2026)Christine A Orengo · University College Lahore4 papers (2024–2026)Lewis Moffat · University College London4 papers (2020–2022)Milot Mirdita · Seoul National University3 papers (2025–2026)Martin Steinegger · Seoul National University3 papers (2025–2026)Ian Sillitoe · Institute of Structural and Molecular Biology3 papers (2024–2026)Vaishali P. Waman · G.S. Science, Arts And Commerce College2 papers (2024–2024)Daniel W A Buchan · University College London2 papers (2024–2025)Jude Wells · University College London2 papers (2024–2024)Janet M. Thornton · European Bioinformatics Institute (EMBL-EBI)1 papers (2022–2022)Chongli Qin · DeepMind1 papers (2020–2020)Steve Crossan · Dyckerhoff (Germany)1 papers (2020–2020)Andrew Senior · University of Oxford1 papers (2020–2020)Vladimir N. Uversky · Hospital for Sick Children1 papers (2014–2014)Koray Kavukcuoglu · DeepMind1 papers (2020–2020)David Silver · Google (United Kingdom)1 papers (2020–2020)