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Bruce A. Edgar

University of Utah · US
Area of research
Immunology · Cell Biology
Research interest
Research interests include Invertebrate Immune Response Mechanisms, Developmental Biology and Gene Regulation, Neurobiology and Insect Physiology Research, and Hippo pathway signaling and YAP/TAZ.
h-index
63
citations
19,897
works
162
NIH funding
primary concept
email

Recent publications

Inter-cell type interactions that control JNK signaling in the Drosophila intestine
Nature Communications 2024cited by 15position: lastdoi
Ceramides Increase Fatty Acid Utilization in Intestinal Progenitors to Enhance Stemness and Increase Tumor Risk
Gastroenterology 2023cited by 37position: middledoi
EGFR signaling activates intestinal stem cells by promoting mitochondrial biogenesis and β-oxidation
Current Biology 2022cited by 53position: lastdoi
Translational control of <i>E2f1</i> regulates the <i>Drosophila</i> cell cycle
Proceedings of the National Academy of Sciences 2022cited by 32position: lastdoi
Cell growth and the cell cycle: New insights about persistent questions
BioEssays 2022cited by 30position: lastdoi
An improved organ explant culture method reveals stem cell lineage dynamics in the adult Drosophila intestine
eLife 2022cited by 23position: lastdoi
Remodelling of oxygen-transporting tracheoles drives intestinal regeneration and tumorigenesis in Drosophila
Nature Cell Biology 2021cited by 63position: middledoi
Age-related changes in polycomb gene regulation disrupt lineage fidelity in intestinal stem cells
eLife 2021cited by 46position: middledoi
Remodeling of oxygen-transporting tracheoles drives intestinal regeneration and tumorigenesis
bioRxiv (Cold Spring Harbor Laboratory) 2021cited by 1position: middledoi
Fitness trade-offs incurred by ovary-to-gut steroid signalling in Drosophila
Nature 2020cited by 165position: lastdoi
Damage sensing by a Nox-Ask1-MKK3-p38 signaling pathway mediates regeneration in the adult Drosophila midgut
Nature Communications 2019cited by 86position: lastdoi
An SH3PX1-Dependent Endocytosis-Autophagy Network Restrains Intestinal Stem Cell Proliferation by Counteracting EGFR-ERK Signaling
Developmental Cell 2019cited by 79position: lastdoi
The role of translationally controlled tumor protein in proliferation of <i>Drosophila</i> intestinal stem cells
Proceedings of the National Academy of Sciences 2019cited by 16position: middledoi
Enhanced expression of thioredoxin‐interacting‐protein regulates oxidative DNA damage and aging
FEBS Letters 2018cited by 55position: middledoi
EGFR-dependent TOR-independent endocycles support Drosophila gut epithelial regeneration
Nature Communications 2017cited by 140position: lastdoi
ATF3 acts as a rheostat to control JNK signalling during intestinal regeneration
Nature Communications 2017cited by 56position: middledoi
Intestinal Stem Cell Pool Regulation in Drosophila
Stem Cell Reports 2017cited by 53position: lastdoi
A Balance of Yki/Sd Activator and E2F1/Sd Repressor Complexes Controls Cell Survival and Affects Organ Size
Developmental Cell 2017cited by 39position: middledoi
Regional Cell-Specific Transcriptome Mapping Reveals Regulatory Complexity in the Adult Drosophila Midgut
Cell Reports 2015cited by 273position: middledoi
Niche appropriation by Drosophila intestinal stem cell tumours
Nature Cell Biology 2015cited by 168position: lastdoi
<scp>FUCCI</scp> sensors: powerful new tools for analysis of cell proliferation
Wiley Interdisciplinary Reviews Developmental Biology 2015cited by 163position: lastdoi
EGFR/Ras Signaling Controls Drosophila Intestinal Stem Cell Proliferation via Capicua-Regulated Genes
PLoS Genetics 2015cited by 144position: lastdoi
Changes in neuronal CycD/Cdk4 activity affect aging, neurodegeneration, and oxidative stress
Aging Cell 2015cited by 12position: lastdoi
Using the Fly-FUCCI System for the Live Analysis of Cell Cycle Dynamics in Cultured Drosophila Cells
Methods in molecular biology 2015cited by 3position: lastdoi
Endocycles: a recurrent evolutionary innovation for post-mitotic cell growth
Nature Reviews Molecular Cell Biology 2014cited by 368position: firstdoi
<i>Escargot</i> maintains stemness and suppresses differentiation in <i>Drosophila</i> intestinal stem cells
The EMBO Journal 2014cited by 142position: lastdoi
Dpp/Gbb signaling is required for normal intestinal regeneration during infection
Developmental Biology 2014cited by 79position: middledoi
Tissue design: How Drosophila tumors remodel their neighborhood
Seminars in Cell and Developmental Biology 2014cited by 27position: lastdoi
Tracking protein turnover and degradation by microscopy: photo-switchable versus time-encoded fluorescent proteins
Open Biology 2014cited by 16position: lastdoi
Hunting complex differential gene interaction patterns across molecular contexts
Nucleic Acids Research 2014cited by 8position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Marco Marchetti · Institute of Human Genetics6 papers (2017–2024)Parthive H. Patel · University of Bristol5 papers (2014–2019)Norman Zielke · University of Helsinki5 papers (2013–2022)Yinhua Jin · East China University of Science and Technology4 papers (2015–2022)Devanjali Dutta · Genmab (Netherlands)4 papers (2014–2015)Peng Zhang · Qingdao University4 papers (2017–2024)Chenge Zhang · University of Utah4 papers (2017–2024)Jerome Korzelius · Heidelberg University3 papers (2014–2021)Jinyi Xiang · Shanghai Jiao Tong University3 papers (2015–2017)Christine Gläßer · University of North Carolina at Chapel Hill3 papers (2014–2015)Laura Buttitta · University of Michigan3 papers (2012–2014)David D. O’Keefe · Salk Institute for Biological Studies3 papers (2012–2014)Aurelio A. Teleman · German Cancer Research Center3 papers (2013–2020)Karsten Gülow · University Hospital Regensburg2 papers (2014–2018)Jonathan Bohlen · Inserm2 papers (2015–2022)Verena Bolender · German Cancer Research Center2 papers (2021–2021) · 2 papers (2021–2021)Mitchell R. Lewis · University of Utah2 papers (2022–2022)Bojana Pavlović · German Cancer Research Center2 papers (2017–2019)Jun Zhou · Taizhou Central Hospital2 papers (2014–2017)