Area of research
Cancer Research · Pulmonary and Respiratory Medicine
Research interest
Research interests include Cancer-related molecular mechanisms research, Ferroptosis and cancer prognosis, Cancer Genomics and Diagnostics, and Bioinformatics and Genomic Networks.
Fibroblast atlas: Shared and specific cell types across tissues
Unveiling a novel cancer hallmark by evaluation of neural infiltration in cancer
SRSF7 promotes pulmonary fibrosis through regulating PKM alternative splicing in lung fibroblasts
Nephronectin (NPNT) is a Crucial Determinant of Idiopathic Pulmonary Fibrosis: Modulating Cellular Senescence via the ITGA3/YAP1 Signaling Axis
Rbms1 promotes pulmonary fibrosis by stabilising Sumo2 mRNA to facilitate Smad4-SUMOylation and fibroblast activation
Translocation of SIRT6 promotes glycolysis reprogramming to exacerbate diabetic angiopathy
GTSE1-expressed osteoblastic cells facilitate formation of pro-metastatic tumor microenvironment in osteosarcoma
Single-cell landscape of intratumoral heterogeneity and tumor microenvironment remolding in pre-nodal metastases of breast cancer
Individualized detection of TMPRSS2-ERG fusion status in prostate cancer: a rank-based qualitative transcriptome signature
Harnessing genetic interactions for prediction of immune checkpoint inhibitors response signature in cancer cells
SNRNP70 regulates the splicing of CD55 to promote osteosarcoma progression
Unraveling immune heterogeneity across pan-cancer and deep insights in lung adenocarcinoma based on alternative splicing
Up-regulated SPP1 increases the risk from IPF to lung cancer via activating the pro-tumor macrophages
Mutant RB1 enhances therapeutic efficacy of PARPis in lung adenocarcinoma by triggering the cGAS/STING pathway
Synthetic viability induces resistance to immune checkpoint inhibitors in cancer cells
Multi-omics integration analysis unveils heterogeneity in breast cancer at the individual level
Identifying metabolic reprogramming phenotypes with glycolysis-lipid metabolism discoordination and intercellular communication for lung adenocarcinoma metastasis
Systematic exploration of the underlying mechanism of gemcitabine resistance in pancreatic adenocarcinoma
StemSC: a cross-dataset human stemness index for single-cell samples
Upregulation of CXCL1 and LY9 contributes to BRCAness in ovarian cancer and mediates response to PARPi and immune checkpoint blockade
LiqBioer: a manually curated database of cancer biomarkers in body fluid
A genetic map of the chromatin regulators to drug response in cancer cells
Identification of mutational signature for lung adenocarcinoma prognosis and immunotherapy prediction
FDRdb: a manually curated database of fibrotic disease–associated RNAome and high-throughput datasets
Individualized lncRNA differential expression profile reveals heterogeneity of breast cancer
A transcriptional signature detects homologous recombination deficiency in pancreatic cancer at the individual level
LncRNA CTD-2528L19.6 prevents the progression of IPF by alleviating fibroblast activation
Discovering a qualitative transcriptional signature of homologous recombination defectiveness for prostate cancer
Revealing biomarkers associated with PARP inhibitors based on genetic interactions in cancer genome
Correction to: LncRNA PTAR promotes EMT and invasionmetastasis in serous ovarian cancer by competitively binding miR-101-3p to regulate ZEB1 expression