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Klaus‐Peter Lesch

University of California, Los Angeles · US
Area of research
Cellular and Molecular Neuroscience · Psychiatry and Mental health
Research interest
Research interests include Neurotransmitter Receptor Influence on Behavior, Attention Deficit Hyperactivity Disorder, Receptor Mechanisms and Signaling, and Stress Responses and Cortisol.
h-index
125
citations
70,232
works
1,300
NIH funding
primary concept
email

Recent publications

Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains
Nature Genetics 2023cited by 731position: middledoi
Author Correction: Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains
Nature Genetics 2023cited by 14position: middledoi
Genetic architecture of 11 major psychiatric disorders at biobehavioral, functional genomic and molecular genetic levels of analysis
Nature Genetics 2022cited by 317position: middledoi
Statistical and functional convergence of common and rare genetic influences on autism at chromosome 16p
Nature Genetics 2022cited by 55position: middledoi
Cadherin-13 is a critical regulator of GABAergic modulation in human stem-cell-derived neuronal networks
Molecular Psychiatry 2021cited by 100position: middledoi
Analysis of structural brain asymmetries in attention‐deficit/hyperactivity disorder in 39 datasets
Journal of Child Psychology and Psychiatry 2021cited by 69position: middledoi
The continued need for animals to advance brain research
Neuron 2021cited by 56position: middledoi
Evidence for similar structural brain anomalies in youth and adult attention-deficit/hyperactivity disorder: a machine learning analysis
Translational Psychiatry 2021cited by 54position: middledoi
Risk variants and polygenic architecture of disruptive behavior disorders in the context of attention-deficit/hyperactivity disorder
Nature Communications 2021cited by 50position: middledoi
A Common CDH13 Variant Is Associated with Low Agreeableness and Neural Responses to Working Memory Tasks in ADHD
Genes 2021cited by 18position: lastdoi
Consortium neuroscience of attention deficit/hyperactivity disorder and autism spectrum disorder: The <scp>ENIGMA</scp> adventure
Human Brain Mapping 2020cited by 115position: middledoi
Shared genetic background between children and adults with attention deficit/hyperactivity disorder
Neuropsychopharmacology 2020cited by 104position: middledoi
The genetic architecture of human brainstem structures and their involvement in common brain disorders
Nature Communications 2020cited by 48position: middledoi
Metabolic, Molecular, and Behavioral Effects of Western Diet in Serotonin Transporter-Deficient Mice: Rescue by Heterozygosity?
Frontiers in Neuroscience 2020cited by 28position: middledoi
Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders
Cell 2019cited by 1,475position: middledoi
Common brain disorders are associated with heritable patterns of apparent aging of the brain
Nature Neuroscience 2019cited by 607position: middledoi
Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder
Nature Genetics 2018cited by 2,304position: middledoi
Live fast, die young? A review on the developmental trajectories of ADHD across the lifespan
European Neuropsychopharmacology 2018cited by 642position: middledoi
The involvement of the canonical Wnt‐signaling receptor <i>LRP5</i> and <i>LRP6</i> gene variants with ADHD and sexual dimorphism: Association study and meta‐analysis
American Journal of Medical Genetics Part B Neuropsychiatric Genetics 2018cited by 30position: middledoi
Subcortical brain volume differences in participants with attention deficit hyperactivity disorder in children and adults: a cross-sectional mega-analysis
The Lancet Psychiatry 2017cited by 874position: middledoi
Discovery of the first genome-wide significant risk loci for ADHD
bioRxiv (Cold Spring Harbor Laboratory) 2017cited by 183position: middledoi
Human subcortical brain asymmetries in 15,847 people worldwide reveal effects of age and sex
Brain Imaging and Behavior 2016cited by 223position: middledoi
Genetic Overlap Between Attention-Deficit/Hyperactivity Disorder and Bipolar Disorder: Evidence From Genome-wide Association Study Meta-analysis
Biological Psychiatry 2016cited by 145position: middledoi
Exome chip analyses in adult attention deficit hyperactivity disorder
Translational Psychiatry 2016cited by 35position: middledoi
Defeat stress in rodents: From behavior to molecules
Neuroscience & Biobehavioral Reviews 2015cited by 227position: middledoi
MicroRNA hsa‐miR‐4717‐5p regulates RGS2 and may be a risk factor for anxiety‐related traits
American Journal of Medical Genetics Part B Neuropsychiatric Genetics 2015cited by 25position: middledoi
Cellular resilience: 5-HT neurons in Tph2−/− mice retain normal firing behavior despite the lack of brain 5-HT
European Neuropsychopharmacology 2015cited by 23position: middledoi
Deuterium content of water increases depression susceptibility: The potential role of a serotonin-related mechanism
Behavioural Brain Research 2014cited by 84position: lastdoi
The epigenome and postnatal environmental influences in psychotic disorders
Social Psychiatry and Psychiatric Epidemiology 2014cited by 35position: middledoi
Genetic variation associated with euphorigenic effects of <i>d</i> -amphetamine is associated with diminished risk for schizophrenia and attention deficit hyperactivity disorder
Proceedings of the National Academy of Sciences 2014cited by 19position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Andreas Reif · Department of Physiological Sciences7 papers (2012–2021)Günter Kenis · European Graduate School of Neuroscience3 papers (2013–2015)Heike Weber · Broad Institute3 papers (2015–2021)Marcel Romanos · Ludwig-Maximilians-Universität München3 papers (2013–2021)Harry W.M. Steinbusch · Maastricht University3 papers (2013–2015)Bart P. F. Rutten · Pontificia Universidad Javeriana3 papers (2013–2015)Stephen V. Faraone · SUNY Upstate Medical University3 papers (2013–2018) · 3 papers (2013–2015)Andreas J. Fallgatter · San Francisco VA Medical Center2 papers (2012–2021) · 2 papers (2021–2021) · 2 papers (2014–2020)Raffaël Kalisch · Karolinska Institutet2 papers (2015–2021) · 2 papers (2015–2016)Manuel Mattheisen · Dalhousie University2 papers (2015–2022)Sven Cichon · Université d'Angers2 papers (2013–2015)Anke Hinney · University of Otago2 papers (2013–2018)Paul Pauli · University Hospital Heidelberg2 papers (2012–2021) · 2 papers (2021–2021)Jim van Os · Technical University of Munich2 papers (2014–2015)Daniel C. Anthony · University of Oxford2 papers (2014–2020)